LAT1 and 4F2hc form a heterodimeric membrane protein complex, which functions as one of
the best characterized amino acid transporters. Since LAT1–4F2hc is required for the …

Cellular thyroid hormone uptake and efflux are mediated by transmembrane transport
proteins. One of these, monocarboxylate transporter 8 (MCT8) is mutated in Allan‐Herndon …

Despite having similar structures, each member of the heteromeric amino acid transporter
(HAT) family shows exquisite preference for the exchange of certain amino acids. Substrate …

Mitochondrion is the powerhouse of the cell. The research of nearly a century has expanded
our understanding of mitochondrion, far beyond the view that mitochondrion is an important …

System T is a Na+-independent transport system that selectively transports aromatic amino
acids. Here, we determined the structure of the human T-type amino-acid transporter-1 …

In all mammalian species, the 20 amino acids of the genetic code are required for net
protein accretion. The nutritional supply of amino acids for growth is defined as the net …

Fear, anxiety, and trauma-related disorders, including post-traumatic stress disorder (PTSD),
are quite common and debilitating, with an estimated lifetime prevalence of~ 28% in …

In the last decade, a lot of amino acid transporters were identified by molecular cloning and
assigned to the classically characterized amino acid transport systems. Among them, ones …

Thyroid hormones (TH) are essential for the development of the human brain, growth and
cellular metabolism. Investigation of TH transporters became one of the emerging fields in …

Cystinuria and lysinuric protein intolerance are inherited aminoacidurias caused by
defective amino-acid transport activities linked to a family of heteromeric amino-acid …