Gut microbiota interact with the brain through systemic chronic inflammation: implications on neuroinflammation, neurodegeneration, and aging

Y Mou, Y Du, L Zhou, J Yue, X Hu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
It has been noticed in recent years that the unfavorable effects of the gut microbiota could
exhaust host vigor and life, yet knowledge and theory are just beginning to be established …

Microbiota and COVID-19: Long-term and complex influencing factors

J Gang, H Wang, X Xue, S Zhang - Frontiers in Microbiology, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). According to the World Health …

Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation

Z Tian, Y Zhang, Z Zheng, M Zhang, T Zhang, J Jin… - Cell host & …, 2022 - cell.com
Abdominal aortic aneurysm (AAA) is an insidious and lethal vascular disease that lacks
effective nonsurgical interventions. Gut microbiota dysbiosis plays key roles in many …

Transplantation of bacteriophages from ulcerative colitis patients shifts the gut bacteriome and exacerbates the severity of DSS colitis

A Sinha, Y Li, MK Mirzaei, M Shamash, R Samadfam… - Microbiome, 2022 - Springer
Abstract Background Inflammatory bowel diseases (IBDs) including Crohn's disease (CD)
and ulcerative colitis (UC) are characterized by chronic and debilitating gut inflammation …

[HTML][HTML] Intestinal virome and therapeutic potential of bacteriophages in liver disease

CL Hsu, Y Duan, DE Fouts, B Schnabl - Journal of hepatology, 2021 - Elsevier
Humans harbour a large quantity of microbes in the intestinal tract and have evolved
symbiotic relationships with many of them. However, several specific bacterial pathobionts …

Immunomodulation by enteric viruses

L Bernard-Raichon, K Cadwell - Annual Review of Virology, 2023 - annualreviews.org
Enteric viruses display intricate adaptations to the host mucosal immune system to
successfully reproduce in the gastrointestinal tract and cause maladies ranging from …

The human gut virome: composition, colonization, interactions, and impacts on human health

E Pargin, MJ Roach, A Skye, B Papudeshi… - Frontiers in …, 2023 - frontiersin.org
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in
many disease states, but it is unknown to what extent the gut virome impacts everyday …

Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants

AHJ Kim, G Armah, F Dennis, L Wang, R Rodgers… - Cell Host & Microbe, 2022 - cell.com
Rotavirus vaccines (RVVs) have substantially diminished mortality from severe rotavirus
(RV) gastroenteritis but are significantly less effective in low-and middle-income countries …

[HTML][HTML] Phage Therapy: Targeting Intestinal Bacterial Microbiota for Treatment of Liver Diseases

J Fujiki, B Schnabl - JHEP Reports, 2023 - Elsevier
Phage therapy has been overshadowed by antibiotics for decades. However, it has been
revitalized as a powerful approach against antimicrobial-resistant bacteria. As the bacterial …

Evaluation of computational phage detection tools for metagenomic datasets

KE Schackart III, JB Graham, AJ Ponsero… - Frontiers in …, 2023 - frontiersin.org
Introduction As new computational tools for detecting phage in metagenomes are being
rapidly developed, a critical need has emerged to develop systematic benchmarks. Methods …