Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators

J Wieseler, A Ellis, A McFadden, K Stone, K Brown… - Brain research, 2017 - Elsevier
Facial allodynia is a migraine symptom that is generally considered to represent a pivotal
point in migraine progression. Treatment before development of facial allodynia tends to be …

From astrocytes to satellite glial cells and back: A 25 year-long journey through the purinergic modulation of glial functions in pain and more

S Ceruti - Biochemical Pharmacology, 2021 - Elsevier
Fundamental progresses have been made in pain research with a comprehensive
understanding of the neuronal pathways which convey painful sensations from the periphery …

Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine

A Franceschini, A Nair, T Bele… - BMC neuroscience, 2012 - Springer
Background Enhanced activity of trigeminal ganglion neurons is thought to underlie
neuronal sensitization facilitating the onset of chronic pain attacks, including migraine …

The effect of orofacial complete Freund's adjuvant treatment on the expression of migraine-related molecules

T Körtési, B Tuka, A Nyári, L Vécsei, J Tajti - The Journal of Headache and …, 2019 - Springer
Background Migraine is a neurovascular primary headache disorder, which causes
significant socioeconomic problems worldwide. The pathomechanism of disease is …

Integrated analysis of microRNA and mRNA expression profiles in the rat spinal cord under inflammatory pain conditions

CC Liu, JT Cheng, TY Li, PH Tan - European Journal of …, 2017 - Wiley Online Library
Recent studies using microarray‐based approaches have demonstrated that micro RNA s
(mi RNA s) are involved in pain processing pathways. However, a significant proportion of …

Lipoic-based TRPA1/TRPV1 antagonist to treat orofacial pain

R Gualdani, S Ceruti, G Magni, D Merli… - ACS Chemical …, 2015 - ACS Publications
Inflammation of the trigeminal nerve is considered one of the most painful conditions known
to humankind. The diagnosis is often difficult; moreover, safe and effective pharmacological …

[PDF][PDF] Orofacial pain and toothache as the sole symptom of an acute myocardial infarction entails a major risk of misdiagnosis and death

M Kreiner, J Okeson, V Tanco… - J Oral Facial Pain …, 2020 - files.jofph.com
Aims: To provide an update of knowledge regarding the clinical presentation and
neurophysiologic aspects of orofacial pain of cardiac origin in the form of a literature review …

A 15-year follow-up of temporomandibular joint symptoms and magnetic resonance imaging findings in whiplash patients: a prospective, controlled study

H Salé, F Bryndahl, A Isberg - Oral surgery, oral medicine, oral pathology …, 2014 - Elsevier
Objective This study aimed to determine the incidence, prevalence, and progression of
temporomandibular joint (TMJ) magnetic resonance (MR) imaging findings and symptoms in …

Micronized palmitoylethanolamide reduces joint pain and glial cell activation

ML Bartolucci, I Marini, F Bortolotti, D Impellizzeri… - Inflammation …, 2018 - Springer
Objective and design Temporomandibular disorder (TMD) is a common painful condition in
the temporomandibular joint (TMJ). Joint inflammation is believed to be a chief cause of pain …

Tumor necrosis factor-Alpha stimulates cytokine expression and transient sensitization of trigeminal nociceptive neurons

ZL Durham, JL Hawkins, PL Durham - Archives of oral biology, 2017 - Elsevier
Objective Elevated levels of tumor necrosis factor-alpha (TNF-α) in the capsule of the
temporomandibular joint (TMJ) are implicated in the underlying pathology of …