The authors present clinical work that links dysfunction of the temporomandibular joint (TMJ)
to a variety of neurological disorders. We demonstrate that mechanical realignment between …

Pain is a common complaint of patients in the dental clinic. Patient with dental orofacial pain
usually presents with hyperalgesia and allodynia. Its management has been a challenge …

The trigeminal system conveys sensory information from extra‐and intracranial structures to
the central nervous system via the fifth cranial nerve. The trigeminal ganglion is located …

Glycans, a major class of biomolecules, are expressed on every cells surface and play an
important role in maintaining health with their perturbation causing disease. Polysialic acid …

Introduction. Trigeminal neuropathic pain caused by damage to the trigeminal nerve is very
intense and extremely stressful compared to other types of neuropathic pain. Animal models …

Sensory ganglia are essential for the transmission of sensory signals from the periphery to
the central nervous system, and abnormal electrical activity in sensory neurons is a major …

Background Trigeminal nerve injury or orofacial inflammation causes severe pain in the
orofacial regions innervated by uninjured nerves or uninflamed tissues as well as injured or …

Migraine is a neurovascular primary headache disorder that affects around 14.4% of the
adult population thereby it causes significant socioeconomic problems worldwide (1). The …

With regards to the laboratory, I would like to thank all the Lundy/El Karim group past and
present for their advice and friendship. I'd like to extend a particular thanks to Orla Dunne for …