Hyperuricemia and its related diseases: mechanisms and advances in therapy

L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Flexible SERS wearable sensor based on nanocomposite hydrogel for detection of metabolites and pH in sweat

W Wang, Y Chen, C Xiao, S Xiao, C Wang… - Chemical Engineering …, 2023 - Elsevier
Flexible wearable sensors can detect analytes continuously, in real time, and non-
invasively, and their application in human health monitoring has received great attention …

Inborn errors of purine salvage and catabolism

M Camici, M Garcia-Gil, S Allegrini, R Pesi… - Metabolites, 2023 - mdpi.com
Cellular purine nucleotides derive mainly from de novo synthesis or nucleic acid turnover
and, only marginally, from dietary intake. They are subjected to catabolism, eventually …

Xanthine Oxidase Inhibitory Peptides from Larimichthys polyactis: Characterization and In Vitro/In Silico Evidence

X Chen, W Guan, Y Li, J Zhang, L Cai - Foods, 2023 - mdpi.com
Hyperuricemia is linked to a variety of disorders that can have serious consequences for
human health. Peptides that inhibit xanthine oxidase (XO) are expected to be a safe and …

High-accuracy renal cell carcinoma discrimination through label-free SERS of Blood serum and multivariate analysis

BA Buhas, V Toma, N Crisan, G Ploussard, TA Maghiar… - Biosensors, 2023 - mdpi.com
Renal cell carcinoma (RCC) represents the sixth most frequently diagnosed cancer in men
and is asymptomatic, being detected mostly incidentally. The apparition of symptoms …

[HTML][HTML] A contrast set mining based approach for cancer subtype analysis

AM Trasierras, JM Luna, S Ventura - Artificial Intelligence in Medicine, 2023 - Elsevier
The task of detecting common and unique characteristics among different cancer subtypes is
an important focus of research that aims to improve personalized therapies. Unlike current …

Gout and colorectal cancer likelihood: Insights from a nested case-control study of the Korean population utilizing the Korean National Health Insurance Service …

MJ Kwon, KM Han, JH Kim, JH Kim, MJ Kim, NY Kim… - Cancers, 2023 - mdpi.com
Simple Summary Using Korean National Health Insurance Service-National Sample Cohort
database, we studied whether patient-specific factors such as age, gender, socioeconomic …

Genome-wide analyses reveals an association between invasive urothelial carcinoma in the Shetland sheepdog and NIPAL1

HG Parker, AC Harris, J Plassais, D Dhawan… - npj Precision …, 2024 - nature.com
Naturally occurring canine invasive urinary carcinoma (iUC) closely resembles human
muscle invasive bladder cancer in terms of histopathology, metastases, response to therapy …

The protective effects of uric acid against myocardial ischemia via the Nrf2 pathway

P Ma, M Zhao, Y Li, G Zhang, Y Ma, Y Shi, P Su… - European Journal of …, 2023 - Elsevier
Uric acid (UA) possesses both pro-and anti-oxidative properties in ischemic heart disease,
but the underlying mechanism remains unclear. We aimed to investigate UA's protective …

Association of serum uric acid and fasting plasma glucose with cognitive function: a cross-sectional study

Z Yuan, H Liu, R Zhou, S Gu, K Wu, Z Huang, Q Zhong… - BMC geriatrics, 2023 - Springer
Background The combined effect of serum uric acid (SUA) and blood glucose on cognition
has not been explored. This study aimed to examine the separate and combined association …