Introduction Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder associated
with cognitive and behavioral impairments and motor symptoms. Magnetic resonance …

Amyotrophic lateral sclerosis causes degeneration of motor neurons, resulting in
progressive muscle weakness and impairment in motor function. Promising drug …

Approximately 80–96% of people with amyotrophic lateral sclerosis (ALS) become unable to
speak during the disease progression. Assessing upper and lower motor neuron impairment …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting
motorneurons of the bulbar, cervical, thoracic, or lumbar segments. Bulbar presentation is a …

Abstract Introduction/Aims Many people living with amyotrophic lateral sclerosis (PALS)
report restrictions in their day‐to‐day communication (communicative participation) …

Automatic speech assessments have the potential to dramatically improve ALS clinical
practice and facilitate patient stratification for ALS clinical trials. Acoustic speech analysis …

Purpose: In this study, we examined the utility of vowel intelligibility testing for assessing the
impact of dysarthria on speech characteristics in people with amyotrophic lateral sclerosis …

Objective There is a need for novel biomarkers that can indicate disease state, project
disease progression, or assess response to treatment for amyotrophic lateral sclerosis (ALS) …

In this study, we describe the responsiveness of timing-related measures extracted from
read speech in persons with ALS (pALS) collected via a remote patient monitoring platform …

Purpose: Traditional health care decision-making models center on clinicians making
decisions for patients/caregivers based on the best available research evidence. However …