Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

We examine the role of dendritic cells subsets in immunity to peripheral infections, with
emphasis on the differences in the regulation of primary and secondary T cell responses to …

Fcγ receptors (FcγR) are cell surface glycoproteins that mediate cellular effector functions of
immunoglobulin G (IgG) antibodies. Genetic variation in FcγR genes can influence …

Antibodies, forming immune complexes with their specific antigen, can cause complete
suppression or several 100-fold enhancement of the antibody response. Immune complexes …

Abstract Glycosylation of IgG Fc domains is a central mechanism in the diversification of
antibody function. Modifications to the core Fc glycan impact antibody function by shifting the …

The aberrant activation of Wnt/β-catenin signaling in tumor cells and immune cells in the
tumor microenvironment (TME) promotes malignant transformation, metastasis, immune …

Several clinical studies done with intravenous immunoglobulin (IVIg)–treated autoimmune
patients as well as several in vitro studies have revealed that IVIg can reduce polyclonal T …

Biodegradable microparticles (MPs) as vaccine adjuvants have sparked the passion of
researchers in recent decades. However, it is still a huge challenge to develop an efficient …

Mast cells (MCs) are immune cells residing in tissues where pathogens are first
encountered. It has been indicated that MCs might also be involved in setting the outcome of …

Recent studies have revealed multiple roles for Fc gamma receptors (FcγRs) in broad
immunity against influenza viruses. Activating FcγR pathways can be harnessed to confer …