Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Abstract Purpose of Review In the last decade many studies have suggested an association
between the altered gut microbiota and multiple systemic diseases including diabetes. In …

The gut–brain axis is a bidirectional communication network connecting the gastrointestinal
tract and central nervous system. The axis keeps track of gastrointestinal activities and …

Lactobacillus rhamnosus GG (LGG) is a well-known probiotic widely used in foods and
drugs. It has been reported that LGG can improve bowel dysfunction in gastrointestinal …

Uridine (UR) is a pyrimidine nucleoside that plays an important role in regulating glucose
and lipid metabolism. The aim of this study was to investigate the effect of UR on obesity, fat …

N-Acetylcysteine (NAC), a well-accepted antioxidant, has been shown to protect against
high fat diet (HFD)-induced obesity-associated non-alcoholic fatty liver disease (NAFLD) in …

The gut microbiota is now recognized as a major contributor to the host's nutrition,
metabolism, immunity, and neurological functions. Imbalanced microbiota (ie, dysbiosis) is …

Oxidative stress is an important factor in the development of type 2 diabetes (T2D) and
associated complications. Unfortunately, most clinical studies have failed to provide …

Excessive adiposity in an obese state is known to drive the onset of metabolic
dysregulations, mostly involving chronic immune activation and oxidative stress. Prolonged …

The gut is a selective barrier that not only allows the translocation of nutrients from food, but
also microbe-derived metabolites to the systemic circulation that flows through the liver …