From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …
modulation of the activity of genes, impacting a variety of homeostatic processes involving …
Long noncoding RNA SLC2A1‐AS1 regulates aerobic glycolysis and progression in hepatocellular carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway
R Shang, M Wang, B Dai, J Du, J Wang… - Molecular …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most lethal malignant diseases worldwide.
Despite advances in the diagnosis and treatment of HCC, its overall prognosis remains …
Despite advances in the diagnosis and treatment of HCC, its overall prognosis remains …
The double-edged sword of H19 lncRNA: Insights into cancer therapy
H19 long non-coding RNA (lncRNA) has many functions in cancer. Some studies have
reported that H19 acts as an oncogene and is involved in cancer progression by activating …
reported that H19 acts as an oncogene and is involved in cancer progression by activating …
[HTML][HTML] Competitive endogenous RNA is an intrinsic component of EMT regulatory circuits and modulates EMT
Y Liu, M Xue, S Du, W Feng, K Zhang, L Zhang… - Nature …, 2019 - nature.com
The competitive endogenous RNA (ceRNA) hypothesis suggests an intrinsic mechanism to
regulate biological processes. However, whether the dynamic changes of ceRNAs can …
regulate biological processes. However, whether the dynamic changes of ceRNAs can …
An updated review of the H19 lncRNA in human cancer: molecular mechanism and diagnostic and therapeutic importance
Accumulating evidence has reported that H19 long non-coding RNA (lncRNA) expression
level is deregulated in human cancer. It has been also demonstrated that de-regulated …
level is deregulated in human cancer. It has been also demonstrated that de-regulated …
[HTML][HTML] LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK
X Si, R Zang, E Zhang, Y Liu, X Shi, E Zhang, L Shao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Breast cancer is a common malignancy in women. Acquisition of drug resistance is one of
the main obstacles encountered in breast cancer therapy. Long non-coding RNA (lncRNA) …
the main obstacles encountered in breast cancer therapy. Long non-coding RNA (lncRNA) …
Long noncoding RNAs: regulation, function and cancer
A Rafiee, F Riazi-Rad, M Havaskary… - … and Genetic Engineering …, 2018 - Taylor & Francis
Long noncoding RNAs (lncRNAs) are non-protein-coding RNA transcripts that exert a key
role in many cellular processes and have potential toward addressing disease etiology …
role in many cellular processes and have potential toward addressing disease etiology …
LncRNA-NEF antagonized epithelial to mesenchymal transition and cancer metastasis via cis-regulating FOXA2 and inactivating Wnt/β-catenin signaling
Emerging evidence indicates that the long noncoding RNAs extensively participate in
cancer progression. Nevertheless, the molecular pathogenesis of how these lncRNAs …
cancer progression. Nevertheless, the molecular pathogenesis of how these lncRNAs …
Long noncoding RNAs in cancer‐immunity cycle
WD Yu, H Wang, QF He, Y Xu… - Journal of cellular …, 2018 - Wiley Online Library
The imbalance of immune status in cancer microenvironment plays an important role in the
development and progression of cancer. Immunotherapy based on this has become an …
development and progression of cancer. Immunotherapy based on this has become an …
Interactions among lncRNAs, miRNAs and mRNA in colorectal cancer
XJ Tang, W Wang, SS Hann - Biochimie, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …
recently emerged as one of the largest and significantly diverse RNA families whereas …