Regulatory roles of long noncoding RNAs implicated in cancer hallmarks
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …
LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy
Background Astrocyte and microglia activation are well-known features of temporal lobe
epilepsy that may contribute to epileptogenesis. However, the mechanisms underlying glia …
epilepsy that may contribute to epileptogenesis. However, the mechanisms underlying glia …
[HTML][HTML] Long non-coding RNAs in colorectal cancer
X Xie, B Tang, YF Xiao, R Xie, BS Li, H Dong, JY Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
Despite substantial progress in understanding the molecular mechanisms and treatment of …
Despite substantial progress in understanding the molecular mechanisms and treatment of …
Identification of the 3-lncRNA signature as a prognostic biomarker for colorectal cancer
S Liu, Q Cao, G An, B Yan, L Lei - International journal of molecular …, 2020 - mdpi.com
Colorectal cancer (CRC) is one of the most common malignant carcinomas in the world, and
metastasis is the main cause of CRC-related death. However, the molecular network …
metastasis is the main cause of CRC-related death. However, the molecular network …
Hypoxia induces H19 expression through direct and indirect Hif-1α activity, promoting oncogenic effects in glioblastoma
W Wu, Q Hu, E Nie, T Yu, Y Wu, T Zhi, K Jiang… - Scientific reports, 2017 - nature.com
H19 expression is elevated in many human tumors including glioblastomas, suggesting an
oncogenic role for the long noncoding RNA; yet the upregulation of H19 in glioblastomas …
oncogenic role for the long noncoding RNA; yet the upregulation of H19 in glioblastomas …
[HTML][HTML] LncRNA MALAT1 exerts oncogenic functions in lung adenocarcinoma by targeting miR-204
J Li, J Wang, Y Chen, S Li, M Jin, H Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that the lncRNAs play a critical role in cancer progression
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …
[HTML][HTML] Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis
T Wu, L Qu, G He, L Tian, L Li, H Zhou, Q Jin, J Ren… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Laryngeal squamous cell carcinoma (LSCC) is a highly aggressive malignant cancer. The
regulation of LSCC progression by long non-coding RNA (lncRNA) was not well understood …
regulation of LSCC progression by long non-coding RNA (lncRNA) was not well understood …
Long non‐coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR‐152
Z Li, Y Li, Y Li, K Ren, X Li, X Han… - Journal of Biochemical …, 2017 - Wiley Online Library
Long non‐coding RNA (lncRNA) H19 in tumors played important roles in various biological
processes. However, the biological role and molecular mechanism of H19 in breast cancer …
processes. However, the biological role and molecular mechanism of H19 in breast cancer …
Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138
J Wu, J Zhao, L Sun, Y Pan, H Wang, WB Zhang - Bone, 2018 - Elsevier
Bone marrow mesenchymal stem cells (BMMSCs) provide the biological basis for bone
reconstruction. Mechanical tension stimulation as a potent modulator is able to promote …
reconstruction. Mechanical tension stimulation as a potent modulator is able to promote …
Long non-coding RNAs and their role in metastasis
UH Weidle, F Birzele, G Kollmorgen… - Cancer genomics & …, 2017 - cgp.iiarjournals.org
The perception of long non-coding RNAs as chunk RNA and transcriptional noise has been
steadily replaced by their role as validated targets for a diverse set of physiological …
steadily replaced by their role as validated targets for a diverse set of physiological …