Regulatory roles of long noncoding RNAs implicated in cancer hallmarks

J Wang, X Zhang, W Chen, X Hu, J Li… - International journal of …, 2020 - Wiley Online Library
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …

LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy

CL Han, M Ge, YP Liu, XM Zhao, KL Wang… - Journal of …, 2018 - Springer
Background Astrocyte and microglia activation are well-known features of temporal lobe
epilepsy that may contribute to epileptogenesis. However, the mechanisms underlying glia …

[HTML][HTML] Long non-coding RNAs in colorectal cancer

X Xie, B Tang, YF Xiao, R Xie, BS Li, H Dong, JY Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the leading causes of cancer-related death worldwide.
Despite substantial progress in understanding the molecular mechanisms and treatment of …

Identification of the 3-lncRNA signature as a prognostic biomarker for colorectal cancer

S Liu, Q Cao, G An, B Yan, L Lei - International journal of molecular …, 2020 - mdpi.com
Colorectal cancer (CRC) is one of the most common malignant carcinomas in the world, and
metastasis is the main cause of CRC-related death. However, the molecular network …

Hypoxia induces H19 expression through direct and indirect Hif-1α activity, promoting oncogenic effects in glioblastoma

W Wu, Q Hu, E Nie, T Yu, Y Wu, T Zhi, K Jiang… - Scientific reports, 2017 - nature.com
H19 expression is elevated in many human tumors including glioblastomas, suggesting an
oncogenic role for the long noncoding RNA; yet the upregulation of H19 in glioblastomas …

[HTML][HTML] LncRNA MALAT1 exerts oncogenic functions in lung adenocarcinoma by targeting miR-204

J Li, J Wang, Y Chen, S Li, M Jin, H Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that the lncRNAs play a critical role in cancer progression
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …

[HTML][HTML] Regulation of laryngeal squamous cell cancer progression by the lncRNA H19/miR-148a-3p/DNMT1 axis

T Wu, L Qu, G He, L Tian, L Li, H Zhou, Q Jin, J Ren… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Laryngeal squamous cell carcinoma (LSCC) is a highly aggressive malignant cancer. The
regulation of LSCC progression by long non-coding RNA (lncRNA) was not well understood …

Long non‐coding RNA H19 promotes the proliferation and invasion of breast cancer through upregulating DNMT1 expression by sponging miR‐152

Z Li, Y Li, Y Li, K Ren, X Li, X Han… - Journal of Biochemical …, 2017 - Wiley Online Library
Long non‐coding RNA (lncRNA) H19 in tumors played important roles in various biological
processes. However, the biological role and molecular mechanism of H19 in breast cancer …

Long non-coding RNA H19 mediates mechanical tension-induced osteogenesis of bone marrow mesenchymal stem cells via FAK by sponging miR-138

J Wu, J Zhao, L Sun, Y Pan, H Wang, WB Zhang - Bone, 2018 - Elsevier
Bone marrow mesenchymal stem cells (BMMSCs) provide the biological basis for bone
reconstruction. Mechanical tension stimulation as a potent modulator is able to promote …

Long non-coding RNAs and their role in metastasis

UH Weidle, F Birzele, G Kollmorgen… - Cancer genomics & …, 2017 - cgp.iiarjournals.org
The perception of long non-coding RNAs as chunk RNA and transcriptional noise has been
steadily replaced by their role as validated targets for a diverse set of physiological …