Single cell computational analysis has emerged as a powerful tool in the field of oncology,
enabling researchers to decipher the complex cellular heterogeneity that characterizes …

Brain organoids hold great potential for modeling human brain development and
pathogenesis. They recapitulate certain aspects of the transcriptional trajectory, cellular …

Background The development of single-cell RNA sequencing (scRNA-seq) has enabled
scientists to catalog and probe the transcriptional heterogeneity of individual cells in …

The single-cell assay for transposase-accessible chromatin using sequencing (scATAC-seq)
technology provides insight into gene regulation and epigenetic heterogeneity at single-cell …

Outer radial glia (oRG) emerge as cortical progenitor cells that support the development of
an enlarged outer subventricular zone (oSVZ) and the expansion of the neocortex. The in …

The rapid accumulation of single-cell RNA-seq data has provided rich resources to
characterize various human cell populations. However, achieving accurate cell-type …

Early characterization of drug targets associated with disease can greatly reduce clinical
failures attributed to lack of safety or efficacy. As single-cell RNA sequencing (scRNA-seq) of …

Experts from 18 consortia are collaborating on the Human Reference Atlas (HRA) which
aims to map the 37 trillion cells in the healthy human body. Information relevant for HRA …

Resident memory T (Trm) cells which are specifically located in non-lymphoid tissues
showed distinct phenotypes and functions compared to circulating memory T cells and were …

Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to construct a reference
3D structural, cellular, and molecular atlas of the healthy adult human body. The HuBMAP …