Context Noninvasive prenatal determination of fetal sex using cell-free fetal DNA provides
an alternative to invasive techniques for some heritable disorders. In some countries this …

Abstract Analysis of circulating tumour DNA (ctDNA), as one type of 'liquid biopsy', has
recently attracted great attention. Researchers are exploring many potential applications of …

BACKGROUND With the advent of massively parallel sequencing (MPS), DNA analysis can
now be performed in a genomewide manner. Recent studies have demonstrated the high …

Background Fetal DNA in maternal urine, if present, would be a valuable source of fetal
genetic material for noninvasive prenatal diagnosis. However, the existence of fetal DNA in …

In spite of numerous publications on potential diagnostic application of circulating DNA and
transrenal nucleic acid (Tr‐NA) analysis, few, if any, tests based on this technology are …

Background Cell-free fetal DNA (cffDNA) can be detected in maternal blood during
pregnancy, opening the possibility of early non-invasive prenatal diagnosis for a variety of …

The initial discovery of cell-free DNA (cfDNA) in 1948 by Mandel and Metais has led to
numerous investigations evaluating the role of cfDNA in various disease states. cfDNA has …

Cancer biomarkers are a promising tool for cancer detection, personalization of therapy, and
monitoring of treatment response or recurrence.“Liquid biopsy” commonly refers to minimally …

Purpose: The existence of transrenal clearance of circulating cell-free DNA is controversial.
In this study, we used NPC as a model to investigate if circulating EBV DNA can be excreted …

In the past decade, cell free DNA, or circulating cell free DNA, or cell free circulating DNA,
isolated from body fluids such as plasma/serum/urine has emerged as an important tool for …