Overview of immunological & virological factors driving the evolution & global spread of SARS-CoV-2 variants
R Ramasamy - Indian Journal of Medical Research, 2023 - journals.lww.com
Abstract The SARS-CoV-2, a highly infectious positive strand RNA virus first identified in
December 2019, has produced multiple genetic variants that have rapidly and sequentially …
December 2019, has produced multiple genetic variants that have rapidly and sequentially …
[HTML][HTML] RT-PCR genotyping assays to identify SARS-CoV-2 variants in England in 2021: a design and retrospective evaluation study
N Bray, W Sopwith, M Edmunds… - The Lancet …, 2024 - thelancet.com
Background Whole-genome sequencing (WGS) is the gold standard diagnostic tool to
identify and genetically characterise emerging pathogen mutations (variants), but cost …
identify and genetically characterise emerging pathogen mutations (variants), but cost …
[HTML][HTML] Significance of wastewater surveillance in detecting the prevalence of SARS-CoV-2 variants and other respiratory viruses in the community–a multi-site …
Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral genome
in wastewater has proven to be useful for tracking the trends of virus prevalence within the …
in wastewater has proven to be useful for tracking the trends of virus prevalence within the …
Data-driven recombination detection in viral genomes
Recombination is a key molecular mechanism for the evolution and adaptation of viruses.
The first recombinant SARS-CoV-2 genomes were recognized in 2021; as of today, more …
The first recombinant SARS-CoV-2 genomes were recognized in 2021; as of today, more …
Emergence of a second SARS‐CoV‐2 variant with a tremendous genetic leap from its ancestors
P Colson, B La Scola, M Beye, J Delerce… - Journal of Medical …, 2023 - Wiley Online Library
The on‐going emergence of the Omicron BA. 2.86 variant is one of the major events in
SARS‐CoV‐2 genetic evolution that remain enigmatic regarding the overall virus mutation …
SARS‐CoV‐2 genetic evolution that remain enigmatic regarding the overall virus mutation …
The return of the “Mistigri”(virus adaptative gain by gene loss) through the SARS‐CoV‐2 XBB. 1.5 chimera that predominated in 2023
Severe acute respiratory syndrome coronavirus 2 XBB. 1.5 is the first recombinant lineage to
predominate at the country and global scales. Very interestingly, like the Marseille‐4B …
predominate at the country and global scales. Very interestingly, like the Marseille‐4B …
Structural basis of main proteases of coronavirus bound to Bofutrelvir
W Wang, P Zeng, T Liu, X Zhou, C Lin, L Guo… - Journal of Molecular …, 2024 - Elsevier
Globally, the continuous spread and evolution of SARS-CoV-2, along with its variants,
profoundly impact human well-being, health, security, and the growth of socio-economic. In …
profoundly impact human well-being, health, security, and the growth of socio-economic. In …
Systematic analysis of SARS-CoV-2 Omicron subvariants' impact on B and T cell epitopes
R Al Khalaf, A Bernasconi, P Pinoli - PloS one, 2024 - journals.plos.org
Introduction Epitopes are specific structures in antigens that are recognized by the immune
system. They are widely used in the context of immunology-related applications, such as …
system. They are widely used in the context of immunology-related applications, such as …
Comprehensive detection and dissection of interlineage recombination events in the SARS-CoV-2 pandemic
The global prevalence of the XBB lineage presents a formidable challenge posed by the
recombinant SARS-CoV-2 virus. The understanding of SARS-CoV-2's recombination …
recombinant SARS-CoV-2 virus. The understanding of SARS-CoV-2's recombination …
Impact of mutations defining SARS-CoV-2 Omicron subvariants BA. 2.12. 1 and BA. 4/5 on Spike function and neutralization
Additional mutations in the viral Spike protein helped the BA. 2.12. 1 and BA. 4/5 SARS-CoV-
2 Omicron subvariants to outcompete the parental BA. 2 subvariant. Here, we determined …
2 Omicron subvariants to outcompete the parental BA. 2 subvariant. Here, we determined …