Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …

Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …

Antisense technology is now beginning to deliver on its promise to treat diseases by
targeting RNA. Nine single-stranded antisense oligonucleotide (ASO) drugs representing …

Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …

In recent decades, obesity has extensively emerged to the level of pandemics. It's
significantly associated with serious co-morbidities that could decrease life quality and even …

Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane
bilayer, secreted by most cells in the body. They carry various molecules, including proteins …

Adenosine deaminase acting on RNA (ADAR) catalyzes the posttranscriptional conversion
of adenosine to inosine in double‐stranded RNA (dsRNA), which can lead to the creation of …

RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …