Thiazole ring—A biologically active scaffold
A Petrou, M Fesatidou, A Geronikaki - Molecules, 2021 - mdpi.com
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …
applications. Its derivatives have a wide range of biological activities such as antioxidant …
Review of the synthesis and biological activity of thiazoles
SH Ali, AR Sayed - Synthetic Communications, 2021 - Taylor & Francis
This study covers the literature documents available on the chemistry of preparation of
thiazoles. Additionally, we cover the biological activities of certain thiazoles. The information …
thiazoles. Additionally, we cover the biological activities of certain thiazoles. The information …
An overview of the synthesis and antimicrobial, antiprotozoal, and antitumor activity of thiazole and bisthiazole derivatives
Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …
QSAR, molecular docking and ADMET properties in silico studies of novel 4, 5, 6, 7-tetrahydrobenzo [D]-thiazol-2-Yl derivatives derived from dimedone as potent anti …
A quantitative structure-activity relationship (QSAR) study is performed on 48 novel 4, 5, 6, 7-
tetrahydrobenzo [D]-thiazol-2 derivatives as anticancer agents capable of inhibiting c-Met …
tetrahydrobenzo [D]-thiazol-2 derivatives as anticancer agents capable of inhibiting c-Met …
Synthesis, anticancer activity and mechanism of action of new thiazole derivatives
TI de Santana, M de Oliveira Barbosa… - European journal of …, 2018 - Elsevier
Thiazole derivatives are recognized to possess various biological activities as antiparasitic,
antifungal, antimicrobial and antiproliferative. The present work reports the synthesis of 22 …
antifungal, antimicrobial and antiproliferative. The present work reports the synthesis of 22 …
Expedition of sulfur‐containing heterocyclic derivatives as cytotoxic agents in medicinal chemistry: A decade update
K Laxmikeshav, P Kumari… - Medicinal Research …, 2022 - Wiley Online Library
This review article proposes a comprehensive report of the design strategies engaged in the
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …
development of various sulfur‐bearing cytotoxic agents. The outcomes of various studies …
New series of thiazole derivatives: synthesis, structural elucidation, antimicrobial activity, molecular modeling and MOE docking
Based on the extensive biological activities of thiazole derivatives against different types of
diseases, we are interested in the effective part of many natural compounds, so we …
diseases, we are interested in the effective part of many natural compounds, so we …
Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination …
Microbial resistance is a big concern worldwide, making the development of new
antimicrobial drugs difficult. The thiazole and pyrazole rings are important heterocyclic …
antimicrobial drugs difficult. The thiazole and pyrazole rings are important heterocyclic …
[HTML][HTML] Antiproliferative activity of thiazole and oxazole derivatives: A systematic review of in vitro and in vivo studies
NY Guerrero-Pepinosa, MC Cardona-Trujillo… - Biomedicine & …, 2021 - Elsevier
Thiazole and oxazole are compounds with a heterocyclic nucleus that have attracted the
attention of medicinal chemistry due to the great variety of biological activities that they …
attention of medicinal chemistry due to the great variety of biological activities that they …
A caryophyllene oxide and other potential anticholinesterase and anticancer agent in Salvia verticillata subsp. amasiaca (Freyn & Bornm.) Bornm. (Lamiaceae)
S Karakaya, SV Yilmaz, Ö Özdemir… - Journal of Essential …, 2020 - Taylor & Francis
In vitro cholinesterase inhibition, antioxidant and anticancer potentials of the essential oils
and extracts of flowers and aerial parts of Salvia verticillata subsp. amasiaca have been …
and extracts of flowers and aerial parts of Salvia verticillata subsp. amasiaca have been …