The mitogen-activated protein kinase (MAPK) signaling pathway is the primary regulatory
module of various cellular processes such as cell proliferation, differentiation, and stress …

Abstract Phosphatidylinositol 3-kinase (PI3K)/AKT pathway regulates cell growth,
proliferation, survival, mobility and invasion. Mitogen-activated protein kinase …

Rheumatoid arthritis is a chronic autoimmune disease characterized by persistent
hyperplasia of the synovial membrane and progressive erosion of articular cartilage …

Precision medicine in oncology is the result of an increasing awareness of patient‐specific
clinical features coupled with the development of genomic‐based diagnostics and targeted …

Over the decades, the exploitation of medicinal plants has been done by numerous
merchandise companies or dealers through various conventional healers in a way to lessen …

Despite increasing amounts of experimental evidence depicting the involvement of non-
coding RNAs in cancer, the study of BRAFV600E-regulated genes has thus far focused …

Malignant melanoma is challenging to treat, and metastatic cases need chemotherapy
strategies. Targeted inhibition of commonly mutant BRAF V600E by inhibitors is efficient but …

The tumor microenvironment is characterized by cancer cell subpopulations with
heterogeneous cell cycle profiles. For example, hypoxic tumor zones contain clusters of …

Objective (s): Naringin has been reported to regulate bone metabolism. However, its effect
on osteogenesis remains unclear. The aim was to investigate the effect of naringin on …

Studies have implicated necroptosis mechanisms in orthopaedic-related diseases, since
necroptosis is a unique regulatory cell death pattern. However, the role of Necroptosis …