Recent studies have shown that immunotherapies and molecular targeted therapies are
effective for advanced melanoma. Non-antigen-specific immunotherapies such as …

Abstract Background Torch ginger (Etlingera elatior, EE) is a ginger plant that found in
Southeast Asia. Previous study showed its flowers and leaves composed of several …

Scaffolding proteins colocalize interacting partners on their surface and facilitate complex
formation. They have multiple domains and motifs, which provide binding sites for various …

Despite significant development of melanoma therapies, death rates remain high.
MicroRNAs, controlling posttranscriptionally gene expression, play role in development of …

Studies have implicated necroptosis mechanisms in orthopaedic-related diseases, since
necroptosis is a unique regulatory cell death pattern. However, the role of Necroptosis …

Mutant KRAS represents one of the most frequently observed oncogenes in NSCLC, yet no
therapies are approved for tumors that express activated KRAS variants. While there is …

Here we present miR-CATCHv2. 0, an implemented experimental method that allows the
identification of the microRNA species directly bound to an RNA of interest. After cross …

The advent of targeted therapies of metastatic melanoma, such as MAPK pathway inhibitors
and immune checkpoint antagonists, has turned dermato‐oncology from the “bad guy” to the …

BAG3 protein, a member of BAG family of co-chaperones, has a pro-survival role in several
tumour types. BAG3 anti-apoptotic properties rely on its characteristic to bind several …

Endoglin overexpression is associated with highly proliferative tumor endothelium and also
with some tumors, including melanoma. Its targeting has anti-tumor effectiveness, which can …