Lipids in atherosclerosis: pathophysiology and the role of calculated lipid indices in assessing cardiovascular risk in patients with hyperlipidemia

M Gaggini, F Gorini, C Vassalle - International journal of molecular …, 2022 - mdpi.com
The role of lipids is essential in any phase of the atherosclerotic process, which is
considered a chronic lipid-related and inflammatory condition. The traditional lipid profile …

The oral microbiome in the pathophysiology of cardiovascular disease

A Tonelli, EN Lumngwena, NAB Ntusi - Nature Reviews Cardiology, 2023 - nature.com
Despite advances in our understanding of the pathophysiology of many cardiovascular
diseases (CVDs) and expansion of available therapies, the global burden of CVD …

The anti-inflammatory effects of a Mediterranean diet: A review

C Itsiopoulos, HL Mayr, CJ Thomas - Current Opinion in Clinical …, 2022 - journals.lww.com
The physiological mechanisms of action of this healthy diet pattern are becoming better
understood to be multisystem and involving the gut. Larger controlled trials investigating …

Hyperlipidemia and hypothyroidism

X Su, H Peng, X Chen, X Wu, B Wang - Clinica Chimica Acta, 2022 - Elsevier
Hypothyroidism is closely associated with increased serum total cholesterol (TC), low-
density lipoprotein cholesterol (LDL-C) and triglyceride (TG). The thyroid gland plays an …

Probing the links: Long non-coding RNAs and NF-κB signalling in atherosclerosis

MS Hussain, O Afzal, G Gupta, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …

The role of peroxisome proliferator‐activated receptor γ in lipid metabolism and inflammation in atherosclerosis

X Yang, D Shang - Cell Biology International, 2023 - Wiley Online Library
Cardiovascular disease events are the result of functional and structural abnormalities in the
arteries and heart. Atherosclerosis is the main cause and pathological basis of …

NF-κB, A potential therapeutic target in cardiovascular diseases

W Cheng, C Cui, G Liu, C Ye, F Shao… - … Drugs and Therapy, 2023 - Springer
Cardiovascular diseases (CVDs) are the leading cause of death globally. Atherosclerosis is
the basis of major CVDs–myocardial ischemia, heart failure, and stroke. Among numerous …

Targeting gut microbiota in aging-related cardiovascular dysfunction: Focus on the mechanisms

S Liu, Y He, Y Zhang, Z Zhang, K Huang, L Deng… - Gut …, 2023 - Taylor & Francis
The global population is aging and age-related cardiovascular disease is increasing. Even
after controlling for cardiovascular risk factors, readmission and mortality rates remain high …

Cardiovascular complications in patients with prostate cancer: Potential molecular connections

S Kakkat, P Pramanik, S Singh, AP Singh… - International Journal of …, 2023 - mdpi.com
Cardiovascular diseases (CVDs) and complications are often seen in patients with prostate
cancer (PCa) and affect their clinical management. Despite acceptable safety profiles and …

[HTML][HTML] Single-cell and spatial transcriptomics: Advances in heart development and disease applications

X Long, X Yuan, J Du - Computational and structural biotechnology journal, 2023 - Elsevier
Current transcriptomics technologies, including bulk RNA-seq, single-cell RNA sequencing
(scRNA-seq), single-nucleus RNA-sequencing (snRNA-seq), and spatial transcriptomics …