Cellular heterogeneity and an immunosuppressive tumour microenvironment are
independent yet synergistic drivers of tumour progression and underlie therapeutic …

Low-grade inflammation is the hallmark of metabolic disorders such as obesity, type 2
diabetes and nonalcoholic fatty liver disease. Emerging evidence indicates that these …

Macrophages populate every organ during homeostasis and disease, displaying features of
tissue imprinting and heterogeneous activation. The disconnected picture of macrophage …

Growing evidence supports the hypothesis that dietary factors may play a role in systemic
low-grade chronic inflammation. Summary evidence from randomized controlled trials has …

Inflammation is a biological response involving immune cells, blood vessels and mediators
induced by endogenous and exogenous stimuli, such as pathogens, damaged cells or …

Over the last years, a growing body of evidence suggests that gut microbial communities
play a fundamental role in many aspects of human health and diseases. The gut microbiota …

Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …

In response to inflammatory stimuli, immune cells reconfigure their metabolism and
bioenergetics to generate energy and substrates for cell survival and to launch immune …

High-fat diet (HFD) leads to systemic low-grade inflammation, which has been involved in
the pathogenesis of diverse metabolic and inflammatory diseases. Colon is thought to be the …

In this fast-food era, people depend on ready-made foods and engage in minimal physical
activities that ultimately change their food habits. Majorities of such foods have harmful …