Recent advances on nitric oxide in the upper airways

M Maniscalco, A Bianco, G Mazzarella… - Current Medicinal …, 2016 - ingentaconnect.com
Exhaled nitric oxide (NO) originates from the upper airways, and takes action, to varying
extents, in regulation, protection and defense, as well as in noxious processes. Nitric oxide …

[HTML][HTML] Role of nasal nitric oxide in primary ciliary dyskinesia and other respiratory conditions in children

S Paternò, L Pisani, S Zanconato, VA Ferraro… - International Journal of …, 2023 - mdpi.com
Nitric oxide (NO) is produced within the airways and released with exhalation. Nasal NO
(nNO) can be measured in a non-invasive way, with different devices and techniques …

[HTML][HTML] NO donors and NO delivery methods for controlling biofilms in chronic lung infections

YM Cai, YD Zhang, L Yang - Applied Microbiology and Biotechnology, 2021 - Springer
Nitric oxide (NO), the highly reactive radical gas, provides an attractive strategy in the control
of microbial infections. NO not only exhibits bactericidal effect at high concentrations but also …

Diagnosis of primary ciliary dyskinesia: searching for a gold standard

JS Lucas, MW Leigh - European Respiratory Journal, 2014 - Eur Respiratory Soc
Significant advances have been made in the diagnosis of patients with primary ciliary
dyskinesia (PCD) including centralised services [ 1–3], European consensus guidelines [4] …

[HTML][HTML] Exhaled molecular profiles in the assessment of cystic fibrosis and primary ciliary dyskinesia

T Paff, MP van der Schee, JMA Daniels, G Pals… - Journal of Cystic …, 2013 - Elsevier
Background Early diagnosis and monitoring of disease activity are essential in cystic fibrosis
(CF) and primary ciliary dyskinesia (PCD). We aimed to establish exhaled molecular profiles …

[HTML][HTML] Diagnosis of primary ciliary dyskinesia: potential options for resource-limited countries

N Rumman, C Jackson, S Collins… - European …, 2017 - Eur Respiratory Soc
Primary ciliary dyskinesia is a genetic disease of ciliary function leading to chronic upper
and lower respiratory tract symptoms. The diagnosis is frequently overlooked because the …

[HTML][HTML] Why, when and how to investigate primary ciliary dyskinesia in adult patients with bronchiectasis

M Contarini, A Shoemark, J Rademacher… - Multidisciplinary …, 2018 - Springer
Bronchiectasis represents the final pathway of several infectious, genetic, immunologic or
allergic disorders. Accurate and prompt identification of the underlying cause is a key …

Complexity, temporal stability, and clinical correlates of airway bacterial community composition in primary ciliary dyskinesia

GB Rogers, MP Carroll, NMM Zain… - Journal of Clinical …, 2013 - Am Soc Microbiol
Primary ciliary dyskinesia (PCD) is a genetic disease characterized by abnormalities in
ciliary function, leading to compromised airway clearance and chronic bacterial infection of …

Diagnostic methods in primary ciliary dyskinesia

JS Lucas, T Paff, P Goggin, E Haarman - Paediatric respiratory reviews, 2016 - Elsevier
Diagnosing primary ciliary dyskinesia is difficult. With no reference standard, a combination
of tests is needed; most tests require expensive equipment and specialist scientists. We …

Primary ciliary dyskinesia: an update on new diagnostic modalities and review of the literature

R Popatia, K Haver, A Casey - Pediatric allergy, immunology, and …, 2014 - liebertpub.com
Primary ciliary dyskinesia (PCD) is a genetic condition affecting approximately 1 in 15,000–
20,000 individuals, and the majority of cases exhibit an autosomal recessive inheritance …