Ferroptosis is an iron-dependent form of regulated cell death with distinct characteristics,
including altered iron homeostasis, reduced defense against oxidative stress, and abnormal …

Iron, as an essential trace element for the organism, is vital for maintaining the organism's
health. Excessive iron can promote reactive oxygen species (ROS) accumulation, thus …

Hydropersulfides (RSSH) are believed to serve important roles in vivo, including as
scavengers of damaging oxidants and electrophiles. The α-effect makes RSSH not only …

Diabetic nephropathy (DN) is known as a major microvascular complication in type 1
diabetes. The effect of insulin treatment alone on controlling blood glucose is unsatisfactory …

As a metabolic disruptor, bisphenol A (BPA) has been widely reported to disrupt lipid
balance. Moreover, BPA has gained significant attention due to its estrogenic activity. While …

Polycystic ovary syndrome (PCOS) is a complex, but relatively common endocrine disorder
associated with chronic anovulation, hyperandrogenism, and micro-polycystic ovaries. In …

Iron is necessary for various critical biological processes, but iron overload is also
dangerous since labile iron is redox-active and toxic. We found that low serum iron and …

A successful pregnancy and the birth of a healthy baby depend to a great extent on the
controlled supply of essential nutrients via the placenta. Iron is essential for mitochondrial …

Ferroptosis is a type of programmed cell death caused by phospholipid peroxidation that
has been implicated as a mechanism in several diseases resulting from ischemic …

Ferroptosis, a form of regulated cell death, was first defined in 2012. Ferroptosis mainly
involves iron-driven lipid peroxidation damage of cells. This process is regulated by iron …