Viral infection is a major contributor to the global cancer burden. Recent advances have
revealed that seven known oncogenic viruses promote tumorigenesis through shared host …

A role for somatic mutations in carcinogenesis is well accepted, but the degree to which
mutation rates influence cancer initiation and development is under continuous debate …

Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV)
infection. The mechanism of HCV‐related lymphoproliferative disorders is not fully …

More than 500 million people worldwide are persistently infected with the hepatitis B virus
(HBV) and/or hepatitis C virus (HCV) and are at risk of developing chronic liver disease …

Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality and has an
increasing incidence worldwide. HCC can be induced by multiple etiologies, is influenced …

Hepatitis C virus (HCV) infected patients are known to be at risk of developing liver
complications ie cirrhosis and liver cancer. However, the risks of morbidity and mortality are …

Reactive oxygen and nitrogen species (ROS and RNS) are produced by metabolism of
normal cells. However, in liver diseases, redox is increased thereby damaging the hepatic …

The AID/APOBECs, a group of cytidine deaminases, represent a somewhat unusual protein
family that can insert mutations in DNA and RNA as a result of their ability to deaminate …

Somatic hypermutation introduces point mutations into immunoglobulin genes in germinal
centre B cells during an immune response. The reaction is initiated by cytosine deamination …

Chromosome translocations between c-myc and immunoglobulin (Ig) are associated with
Burkitt's lymphoma in humans and with pristane-and IL6-induced plasmacytomas in mice …