[HTML][HTML] Estrogen signaling in endometrial cancer: a key oncogenic pathway with several open questions

AC Rodriguez, Z Blanchard, KA Maurer, J Gertz - Hormones and Cancer, 2019 - Springer
Endometrial cancer is the most common gynecological cancer in the developed world, and it
is one of the few cancer types that is becoming more prevalent and leading to more deaths …

[HTML][HTML] Role of leptin and adiponectin in endometrial cancer

A Słabuszewska-Jóźwiak, A Lukaszuk… - International journal of …, 2022 - mdpi.com
Endometrial cancer is the most common malignancy of the female genital tract. Obesity is a
strong risk factor for endometrial cancer. Adipose tissue is an active endocrine organ that …

Use of straighteners and other hair products and incident uterine cancer

CJ Chang, KM O'Brien, AP Keil… - JNCI: Journal of the …, 2022 - academic.oup.com
Background Hair products may contain hazardous chemicals with endocrine-disrupting and
carcinogenic properties. Previous studies have found hair product use to be associated with …

Evaluation of endometrial carcinoma prognostic immunohistochemistry markers in the context of molecular classification

AN Karnezis, S Leung, J Magrill… - The Journal of …, 2017 - Wiley Online Library
Molecular subclassification of endometrial carcinoma (EC) with Proactive Molecular Risk
Classifier for Endometrial Cancer (ProMisE) identifies four subtypes [DNA polymerase …

[HTML][HTML] Estrogen receptors-mediated apoptosis in hormone-dependent cancers

A Chimento, A De Luca, P Avena, F De Amicis… - International journal of …, 2022 - mdpi.com
It is known that estrogen stimulates growth and inhibits apoptosis through estrogen receptor
(ER)-mediated mechanisms in many cancer cell types. Interestingly, there is strong evidence …

[HTML][HTML] A Decade of Therapeutic Challenges in Synchronous Gynecological Cancers from the Bucharest Oncological Institute

L Simion, E Chitoran, C Cirimbei, DC Stefan, A Neicu… - Diagnostics, 2023 - mdpi.com
The aim of our study is to present the particularities of a specific subset of gynecological
cancer patients in Romania. We present a review of synchronous gynecological neoplasia …

[HTML][HTML] Mesonephric-like adenocarcinoma of the uterine corpus: Comprehensive immunohistochemical analyses using markers for mesonephric, endometrioid and …

H Kim, K Na, GE Bae, HS Kim - Diagnostics, 2021 - mdpi.com
Mesonephric-like adenocarcinoma (MLA) of the uterine corpus is a rare but distinct
malignant tumor of the female genital tract, demonstrating a characteristic morphology and …

[HTML][HTML] Estrogen receptor, progesterone receptor, and HER2 receptor markers in endometrial cancer

C Wang, DA Tran, MZ Fu, W Chen, SW Fu, X Li - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Background: Endometrial cancer (EC) is a major gynecologic adenocarcinoma that arises
from the endometrium. While the incidence of EC is on the rise worldwide, survivorship and …

Estrogen receptors as potential therapeutic target in endometrial cancer

P Guha, K Sen, P Chowdhury… - Journal of Receptors and …, 2023 - Taylor & Francis
Endometrial cancer (EC) is one of the most common gynecological carcinomas in both
developed and developing countries. Majority of the gynecological malignancies are …

Contemporary use of hormonal therapy in endometrial cancer: a literature review

A Kailasam, C Langstraat - Current Treatment Options in Oncology, 2022 - Springer
Opinion statement Most endometrial cancers are estrogen receptor and progesterone
receptor positive. Hormonal therapy in endometrial cancer is best used in patients with low …