Treatment of node-positive endometrial cancer: chemotherapy, radiation, immunotherapy, and targeted therapy

EA Tubridy, NK Taunk, EM Ko - Current Treatment Options in Oncology, 2024 - Springer
Opinion Statement The standard of treatment for node-positive endometrial cancer (FIGO
Stage IIIC) in North America has been systemic therapy with or without additional external …

Endometrium and steroids, a pathologic overview

F Plaza-Parrochia, C Romero, L Valladares, M Vega - Steroids, 2017 - Elsevier
Normal endometrial function requires of cell proliferation and differentiation; therefore,
disturbances in these processes could lead to pathological entities such as hyperplasia and …

Low-dose bisphenol a in a rat model of endometrial cancer: a CLARITY-BPA study

YK Leung, J Biesiada, V Govindarajah… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Bisphenol A (BPA) is known to be biologically active in experimental models
even at low levels of exposure. However, its impact on endometrial cancer remains unclear …

Differential outcomes and immune checkpoint inhibitor response among endometrial cancer patients with MLH1 hypermethylation versus MLH1 “Lynch-like” mismatch …

MD Toboni, S Wu, A Farrell, J Xiu, JR Ribeiro… - Gynecologic …, 2023 - Elsevier
Objectives To identify differential survival outcomes and immune checkpoint inhibitor (ICI)
response in MLH1 hypermethylated versus MLH1 mutated (“Lynch-like”) endometrial tumors …

Estrogen receptors as potential therapeutic target in endometrial cancer

P Guha, K Sen, P Chowdhury… - Journal of Receptors and …, 2023 - Taylor & Francis
Endometrial cancer (EC) is one of the most common gynecological carcinomas in both
developed and developing countries. Majority of the gynecological malignancies are …

Lipoxin A4 Suppresses IL-1β-Induced Cyclooxygenase-2 Expression Through Inhibition of p38 MAPK Activation in Endometriosis

S Dai, M Zhu, R Wu, D Lin, Z Huang… - Reproductive …, 2019 - journals.sagepub.com
Endometriosis is an inflammation-dependent gynecologic disorder. Increased
cyclooxygenase-2 (COX-2) expression plays an important role in the development and …

Do estrogen, progesterone, P53 and Ki67 receptor ratios determined from curettage materials in endometrioid-type endometrial carcinoma predict lymph node …

V Gülseren, M Kocaer, İA Özdemir, İ Çakır… - Current Problems in …, 2020 - Elsevier
Abstract Aim: Estrogen receptor (ER), progesterone receptor (PR), and Ki-67 and P53
receptor levels in endometrial curettage material were investigated for their ability to predict …

Investigation of circular RNA transcriptome in obesity-related endometrial cancer

K Takenaka, EM Olzomer, KL Hoehn, A Curry-Hyde… - Gene, 2023 - Elsevier
The present study has investigated the circular RNA (circRNA) transcriptome of twenty
obese and postmenopausal women, recruited in Australia, with endometrial cancer (EC) …

Targeting epigenetic regulators for endometrial cancer therapy: Its molecular biology and potential clinical applications

F Inoue, K Sone, Y Toyohara, Y Takahashi… - International Journal of …, 2021 - mdpi.com
Endometrial cancer is one of the most frequently diagnosed gynecological malignancies
worldwide. However, its prognosis in advanced stages is poor, and there are only few …

Neural plasticity of the uterus: New targets for endometrial cancer?

P Español, R Luna, C Soler, P Caruana… - Women's …, 2022 - journals.sagepub.com
Endometrial carcinoma is the most common gynecological malignancy in Western countries
and is expected to increase in the following years because of the high index of obesity in the …