Effects and mechanisms of berberine-loaded tetrahedral framework nucleic acids on osteoporosis

W Zhang, C Guo, D Yao, W Lan, M Zhou… - Journal of Materials …, 2024 - pubs.rsc.org
Osteoporosis is a disease that plagues the world, the complications of which, spinal
fractures and hip fractures, seriously endanger the health of the elderly. At present, the main …

Convenient synthesis and X-ray determination of 2-amino-6 H-1, 3, 4-thiadiazin-3-ium bromides endowed with antiproliferative activity

HN Tawfeek, A Abdelmoez, KA Dahlous… - RSC …, 2024 - pubs.rsc.org
A new series of 1, 3, 4-thiadiazin-3-ium bromide derivatives 9a–g were prepared as a six-
member ring by interactions between 4-substituted thiosemicarbazides 8a–e and α-halo …

Discovery of new Schiff bases of the disalicylic acid scaffold as DNA gyrase and topoisomerase IV inhibitors endowed with antibacterial properties

LH Al-Wahaibi, MA Mahmoud, HA Alzahrani… - Frontiers in …, 2024 - frontiersin.org
DNA gyrase and topoisomerase IV show great potential as targets for antibacterial
medicines. In recent decades, various categories of small molecule inhibitors have been …