The development of brain metastasis (BM) of breast cancer is usually a late event with
deleterious effect on the prognosis. Treatment options for intracerebral seeding of breast …

The medicinal use of aspirin stretches back to ancient times, before it was manufactured in
its pure form in the late 19th century. Its accepted mechanistic target, cyclooxygenase (COX) …

Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

Cancer is a leading cause of death worldwide. The expression of COX-2 and prostaglandins
has not only been associated with various types of cancer but is also directly proportional to …

Introduction: Radix Glycyrrhiza has been used in China for thousand years to treat cancer.
However, focus on its tumor-suppressing mechanism has been concentrated on its effect on …

Metastasis is the major cause of death in breast cancer patients. In this study, we
investigated the effects of baicalin, a natural compound, on cell migration, invasion and …

Background: Matrix metalloproteinase 9 (MMP-9) is related to tumor invasion and
metastasis. However, the role of MMP-9 expression in breast cancer survival remains …

We investigated mechanisms of pancreatic cancer metastasis and defined the biological
role of miR-29c in pancreatic cancer metastasis. After two rounds of cell selection in vivo …

Background Cyclooxygenases (COX) play a key role in prostaglandin metabolism and are
important for tumor development and progression. The aim of this study was to analyze the …

There is a general consensus that breast cancer is a rising trend disease in the world. It is
one of the most common cancer types and is the leading cause of death among women's …