Neurotoxicity in acute and repeated organophosphate exposure

SX Naughton, AV Terry Jr - Toxicology, 2018 - Elsevier
The term organophosphate (OP) refers to a diverse group of chemicals that are found in
hundreds of products worldwide. As pesticides, their most common use, OPs are clearly …

Neurotoxic effects of organophosphorus pesticides and possible association with neurodegenerative diseases in man: A review

M Jokanović - Toxicology, 2018 - Elsevier
In this article the neurotoxic disorders appearing in patients exposed to organophosphorus
pesticides and known mechanisms involved are reviewed. Organophosphorus compounds …

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—a mechanistic approach

MT Baltazar, RJ Dinis-Oliveira, M de Lourdes Bastos… - Toxicology letters, 2014 - Elsevier
The etiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. The role of pesticide …

Systematic review of biomonitoring studies to determine the association between exposure to organophosphorus and pyrethroid insecticides and human health …

M Koureas, A Tsakalof, A Tsatsakis… - Toxicology letters, 2012 - Elsevier
For the appropriate protection of human health it is necessary to accurately estimate the
health effects of human exposure to toxic compounds. In the present review, epidemiological …

The association between toxic pesticide environmental exposure and Alzheimer's disease: A scientometric and visualization analysis

Y Li, R Fang, Z Liu, L Jiang, J Zhang, H Li, C Liu, F Li - Chemosphere, 2021 - Elsevier
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. The
association between environmental factors (eg, pesticide) and AD has attracted …

Chronic exposure to organophosphate (OP) pesticides and neuropsychological functioning in farm workers: a review

MT Muñoz-Quezada, BA Lucero… - … of occupational and …, 2016 - Taylor & Francis
Background: Previous studies have demonstrated that acute poisoning from exposure to
organophosphate (OP) pesticides in agricultural workers causes adverse health effects …

Functional consequences of repeated organophosphate exposure: potential non-cholinergic mechanisms

AV Terry Jr - Pharmacology & therapeutics, 2012 - Elsevier
The class of chemicals known as the “organophosphates”(OPs) comprises many of the most
common agricultural and commercial pesticides that are used worldwide as well as the …

Mechanisms of organophosphate neurotoxicity

YH Tsai, PJ Lein - Current opinion in toxicology, 2021 - Elsevier
The canonical mechanism of organophosphate (OP) neurotoxicity is the inhibition of
acetylcholinesterase (AChE). However, multiple lines of evidence suggest that mechanisms …

A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation

CN Banks, PJ Lein - Neurotoxicology, 2012 - Elsevier
Organophosphorus (OP) nerve agents and pesticides inhibit acetylcholinesterase (AChE),
and this is thought to be a primary mechanism mediating the neurotoxicity of these …

Multiple neurological effects associated with exposure to organophosphorus pesticides in man

M Jokanović, P Oleksak, K Kuca - Toxicology, 2023 - Elsevier
This article reviews available data regarding the possible association of organophosphorus
(OP) pesticides with neurological disorders such as dementia, attention deficit hyperactivity …