Molecular chemoprevention by selenium: a genomic approach

K El-Bayoumy, R Sinha - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Basic research and clinical chemoprevention trials support the protective role of selenium in
cancer prevention but the mechanisms based on the molecular level remain to be fully …

Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus …

MA Azuine, H Tokuda, J Takayasu, F Enjyo… - Pharmacological …, 2004 - Elsevier
In continuation of our search for novel agents, we have investigated 29 phenothiazines and
related tri-heterocyclic compounds as potential cancer chemopreventive agents in a short …

Chemomodulatory efficacy of basil leaf (Ocimum basilicum) on drug metabolizing and antioxidant enzymes, and on carcinogen-induced skin and forestomach …

T Dasgupta, AR Rao, PK Yadava - Phytomedicine, 2004 - Elsevier
Basil or sweet basil (Ocimum basilicum) is cultivated throughout India and is known for its
medicinal value. The effects of doses of 200 and 400 mg/kg body weight of hydroalcoholic …

Chemopreventive potential of Azadirachta indica (Neem) leaf extract in murine carcinogenesis model systems

T Dasgupta, S Banerjee, PK Yadava, AR Rao - Journal of …, 2004 - Elsevier
Numerous laboratory studies reveal that various naturally occurring dietary substances can
modify the patho-physiological process of various metabolic disorders and can be an …

Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway

ML Lin, YC Lu, JG Chung, YC Li, SG Wang… - Cancer letters, 2010 - Elsevier
Aloe-emodin (AE), a natural, biologically active compound from the rhizome of Rheum
palmatum, has been shown to induce apoptosis in several cancer cell lines in vitro …

Roots of Withania somnifera Inhibit Forestomach and Skin Carcinogenesis in Mice

B Padmavathi, PC Rath, AR Rao… - Evidence‐Based …, 2005 - Wiley Online Library
We evaluated the cancer chemopreventive efficacy of the Withania somnifera root, which
has been used in the Indian traditional medicine system for many centuries for the treatment …

Resveratrol-induced apoptosis in human T-cell acute lymphoblastic leukaemia MOLT-4 cells

V Cecchinato, R Chiaramonte, M Nizzardo… - Biochemical …, 2007 - Elsevier
Resveratrol (RES) is a natural occurring phytoalexin that has been shown to have
chemopreventive activity. Resveratrol acts both by suppressing cell proliferation and …

Down‐regulation of MMP‐2 through the p38 MAPK‐NF‐κB‐dependent pathway by aloe‐emodin leads to inhibition of nasopharyngeal carcinoma cell invasion

ML Lin, YC Lu, JG Chung, SG Wang… - Molecular …, 2010 - Wiley Online Library
Abstract Aloe‐emodin (AE), extracted from the rhizome of Rheum palmatum, has an anti‐
proliferative effect on different human cancer cell lines. Nonetheless, the underlying …

[HTML][HTML] Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation

N Wang, Z Wang, Y Wang, X Xie, J Shen, C Peng… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Breast cancer stem cells (CSCs) are considered as the root of mammary tumorigenesis.
Previous studies have demonstrated that ISL efficiently limited the activities of breast CSCs …

Cancer chemoprevention using natural vitamin D and synthetic analogs

KZ Guyton, TW Kensler… - Annual review of …, 2001 - annualreviews.org
Substantial epidemiologic data support a role for vitamin D in cancer prevention. However,
dose-limiting hypercalcemic effects have proved a major obstacle to the development of …