Pancreatic KCa3.1 channels in health and disease
B Soret, J Hense, S Lüdtke, I Thale, A Schwab… - Biological …, 2023 - degruyter.com
Ion channels play an important role for regulation of the exocrine and the endocrine
pancreas. This review focuses on the Ca2+-regulated K+ channel KCa3. 1, encoded by the …
pancreas. This review focuses on the Ca2+-regulated K+ channel KCa3. 1, encoded by the …
Indomethacin prevents TGF-β-induced epithelial-to-mesenchymal transition in pancreatic cancer cells; evidence by Raman spectroscopy
Pancreatic ductal adenocarcinoma (PDAC) has a very low survival rate due to the late
detection and poor response to chemotherapy. Epithelial-to-mesenchymal transition (EMT) …
detection and poor response to chemotherapy. Epithelial-to-mesenchymal transition (EMT) …
Studies on Treatment Within the Scope of Medical Biotechnology for Pancreatic Diseases
D Aylar, A Karatug Kacar - Molecular Biotechnology, 2024 - Springer
The pancreas is made of two compartments: the exocrine pancreas, a source of digestive
enzymes, and the endocrine islets which produce vital hormones. Distinct diseases could …
enzymes, and the endocrine islets which produce vital hormones. Distinct diseases could …
Characterization and comparison of insulinoma tumor model and pancreatic damage caused by the tumor, and identification of possible markers
Insulinoma is a neuroendocrine tumor. It arises from the uncontrolled proliferation of
pancreatic β cells. In this study, we created an insulinoma tumor model in nude mice. INS-1 …
pancreatic β cells. In this study, we created an insulinoma tumor model in nude mice. INS-1 …
Exploring dual effects of dinutuximab beta on cell death and proliferation of insulinoma
A Karatug Kacar - Chemical Biology & Drug Design, 2024 - Wiley Online Library
Insulinoma INS‐1 cells are pancreatic beta cell tumors. Dinutuximab beta (DB) is a
monoclonal antibody used in the treatment of neuroblastoma. The aim of this study is to …
monoclonal antibody used in the treatment of neuroblastoma. The aim of this study is to …
Dinutuximab beta-targeted therapy kills beta-cell tumors of the pancreas
A Karatug Kacar, Z Adıguzel - Holistic Integrative Oncology, 2023 - Springer
Purpose Dinutuximab beta is a monoclonal antibody used only in glioblastoma.
Streptozotocin is an agent that is particularly toxic to pancreatic beta cells. Dinutuximab beta …
Streptozotocin is an agent that is particularly toxic to pancreatic beta cells. Dinutuximab beta …
Dinutuximab Beta-Targeted Immunotherapy Kills Pancreatic Beta Cell Tumors
AK Kacar, Z Adıguzel - 2022 - researchsquare.com
Dinutuximab beta is the first monoclonal antibody that used for the treatment of
neuroblastoma. The aim of this study is to investigate the effects of Dinutuximab beta, whose …
neuroblastoma. The aim of this study is to investigate the effects of Dinutuximab beta, whose …