Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling

N Saunders, B Monel, N Cayet, L Archetti… - Nature …, 2024 - nature.com
Assessing the impact of SARS-CoV-2 on organelle dynamics allows a better understanding
of the mechanisms of viral replication. We combine label-free holotomographic microscopy …

Bayesian networks in renewable energy systems: A bibliographical survey

M Borunda, OA Jaramillo, A Reyes… - … and Sustainable Energy …, 2016 - Elsevier
For the last years, the research and development in the field of Renewable Energy has been
growing due to the need of Renewable Energy as an extended and reliable source of …

Antibiotic combination efficacy (ACE) networks for a Pseudomonas aeruginosa model

C Barbosa, R Beardmore, H Schulenburg… - PLoS biology, 2018 - journals.plos.org
The spread of antibiotic resistance is always a consequence of evolutionary processes. The
consideration of evolution is thus key to the development of sustainable therapy. Two main …

Inferring causal relationships among different histone modifications and gene expression

H Yu, S Zhu, B Zhou, H Xue, JDJ Han - Genome research, 2008 - genome.cshlp.org
Histone modifications are major epigenetic factors regulating gene expression. They play
important roles in maintaining stem cell pluripotency and in cancer pathogenesis. Different …

AtPID: Arabidopsis thaliana protein interactome database—an integrative platform for plant systems biology

J Cui, P Li, G Li, F Xu, C Zhao, Y Li, Z Yang… - Nucleic acids …, 2007 - academic.oup.com
Abstract Arabidopsis thaliana Protein Interactome Database (AtPID) is an object database
that integrates data from several bioinformatics prediction methods and manually collected …

Reverse engineering of gene regulatory networks

KH Cho, SM Choo, SH Jung, JR Kim, HS Choi, J Kim - IET Systems Biology, 2007 - IET
Systems biology is a multi-disciplinary approach to the study of the interactions of various
cellular mechanisms and cellular components. Owing to the development of new …

Insights into protein–protein interfaces using a Bayesian network prediction method

JR Bradford, CJ Needham, AJ Bulpitt… - Journal of molecular …, 2006 - Elsevier
Identifying the interface between two interacting proteins provides important clues to the
function of a protein, and is becoming increasing relevant to drug discovery. Here, surface …

Environmental enrichment reverses histone methylation changes in the aged hippocampus and restores age-related memory deficits

SJ Morse, AA Butler, RL Davis, IJ Soller, FD Lubin - Biology, 2015 - mdpi.com
A decline in long-term memory (LTM) formation is a common feature of the normal aging
process, which corresponds with abnormal expression of memory-related genes in the aged …

Global gene expression and focused knockout analysis reveals genes associated with fungal fruiting body development in Neurospora crassa

Z Wang, F Lopez-Giraldez, N Lehr, M Farré… - Eukaryotic …, 2014 - Am Soc Microbiol
Fungi can serve as highly tractable models for understanding genetic basis of sexual
development in multicellular organisms. Applying a reverse-genetic approach to advance …

Industrializing AI-powered drug discovery: lessons learned from the Patrimony computing platform

M Guedj, J Swindle, A Hamon, S Hubert… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction As a mid-size international pharmaceutical company, we initiated 4 years ago
the launch of a dedicated high-throughput computing platform supporting drug discovery …