To immunosuppress: whom, when and how? That is the question with COVID-19
KL Winthrop, X Mariette - Annals of the rheumatic diseases, 2020 - ard.bmj.com
In ARD, Ramiro et al report a number of sophisticated primary and sensitivity analyses from
an observational cohort study conducted in the Netherlands during the height of the COVID …
an observational cohort study conducted in the Netherlands during the height of the COVID …
Tocilizumab in coronavirus disease 2019-related critical illness: a propensity matched analysis
Objectives: The primary objective was to evaluate ICU mortality at 28 days in patients with
severe hypoxemic respiratory failure due to coronavirus disease 2019 infection who …
severe hypoxemic respiratory failure due to coronavirus disease 2019 infection who …
Angiotensin enzyme inhibitors and angiotensin receptor blockers as protective factors in COVID-19 mortality: a retrospective cohort study
Targeting the renin-angiotensin system is proposed to affect mortality due to coronavirus
disease 2019 (COVID-19). We aimed to compare the mortality rates in COVID-19 patients …
disease 2019 (COVID-19). We aimed to compare the mortality rates in COVID-19 patients …
[HTML][HTML] Treatment with Tocilizumab in Adult Patients with Moderate to Critical COVID‐19 Pneumonia: A Single‐Center Retrospective Study
Objectives This study aimed to assess if tocilizumab (TCZ) timing is associated with
improved survival. Material and methods Data obtained from adult patients with …
improved survival. Material and methods Data obtained from adult patients with …
Mortality and pulmonary embolism in acute respiratory distress syndrome from COVID-19 vs. non-COVID-19
DJ Kutsogiannis, A Alharthy, A Balhamar… - Frontiers in …, 2022 - frontiersin.org
Purpose There may be a difference in respiratory mechanics, inflammatory markers, and
pulmonary emboli in COVID-19 associated ARDS vs. ARDS from other etiologies. Our …
pulmonary emboli in COVID-19 associated ARDS vs. ARDS from other etiologies. Our …
Interleukin‐6 inhibitory effect of natural product naringenin compared to a synthesised monoclonal antibody against life‐threatening COVID‐19
M AmeliMojarad… - Reviews in Medical …, 2023 - Wiley Online Library
Abstract Coronavirus Disease 2019 (COVID‐19) has become a global pandemic in 2020
with high patient mortality due to acute respiratory distress syndrome which is possibly …
with high patient mortality due to acute respiratory distress syndrome which is possibly …
Anti-inflammatory properties of drugs used to control COVID-19 and their effects on the renin-angiotensin system and angiotensin-converting enzyme-2
H Gilzad-Kohan, F Jamali - Journal of Pharmacy & …, 2020 - journals.library.ualberta.ca
COVID-19 infection is associated with systemic inflammation, and sometimes
hyperinflammatory responses with cytokine storm. This plays a major role in COVID-19 …
hyperinflammatory responses with cytokine storm. This plays a major role in COVID-19 …
Administration timing and efficacy of tocilizumab in patients with COVID-19 and elevated IL-6
P Li, Z Lu, Q Li, Z Wang, Y Guo, C Cai… - Frontiers in molecular …, 2021 - frontiersin.org
Background Tocilizumab (TCZ), an interleukin-6 receptor antibody, has previously been
used for treating patients with the coronavirus disease 2019 (COVID-19), but there is a lack …
used for treating patients with the coronavirus disease 2019 (COVID-19), but there is a lack …
A randomized double-blinded placebo controlled trial of clazakizumab for the treatment of COVID-19 pneumonia with hyperinflammation
BE Lonze, P Spiegler, RN Wesson… - Critical care …, 2022 - journals.lww.com
OBJECTIVES: We designed this study to test whether clazakizumab, a direct interleukin-6
inhibitor, benefits patients hospitalized with severe or critical COVID-19 disease …
inhibitor, benefits patients hospitalized with severe or critical COVID-19 disease …
Serotype and clonal distribution dynamics of invasive pneumococcal strains after PCV13 introduction (2011-2016): Surveillance data from 23 sites in Catalonia, Spain
G Ludwig, S Garcia-Garcia, M Lanaspa, P Ciruela… - PLoS …, 2020 - journals.plos.org
Background The objective of this study is to describe incidence and shifts of serotype and
clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups …
clonal distribution of invasive Streptococcus pneumoniae strains in four different age groups …