[HTML][HTML] Engineering precision nanoparticles for drug delivery

MJ Mitchell, MM Billingsley, RM Haley… - Nature reviews drug …, 2021 - nature.com
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …

Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery

W Ho, M Gao, F Li, Z Li, XQ Zhang… - Advanced healthcare …, 2021 - Wiley Online Library
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …

Material design for lymph node drug delivery

A Schudel, DM Francis, SN Thomas - Nature Reviews Materials, 2019 - nature.com
A significant fraction of the total immune cells in the body are located in several hundred
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …

[HTML][HTML] Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy

X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive Materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

[HTML][HTML] Emerging vaccine nanotechnology: from defense against infection to sniping cancer

C Feng, Y Li, BE Ferdows, DN Patel, J Ouyang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Looking retrospectively at the development of humanity, vaccination is an unprecedented
medical landmark that saves lives by harnessing the human immune system. During the …

Mesoporous silica as a versatile platform for cancer immunotherapy

TL Nguyen, Y Choi, J Kim - Advanced Materials, 2019 - Wiley Online Library
Immunotherapy has been recognized for decades as a promising therapeutic method for
cancer treatment. To enhance host immune responses against cancer, antigen‐presenting …

[HTML][HTML] Bacterial outer membrane vesicle based versatile nanosystem boosts the efferocytosis blockade triggered tumor-specific immunity

WR Zhuang, Y Wang, W Nie, Y Lei, C Liang… - Nature …, 2023 - nature.com
Efferocytosis inhibition is emerging as an attractive strategy for antitumor immune therapy
because of the subsequent leak of abundant immunogenic contents. However, the practical …

Nanovaccine‐based strategies to overcome challenges in the whole vaccination cascade for tumor immunotherapy

L Qin, H Zhang, Y Zhou, CS Umeshappa, H Gao - Small, 2021 - Wiley Online Library
Nanovaccine‐based immunotherapy (NBI) has received greater attention recently for its
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …

Lymphatic targeting by albumin-hitchhiking: applications and optimisation

M Abdallah, OO Müllertz, IK Styles, A Mörsdorf… - Journal of Controlled …, 2020 - Elsevier
The lymphatic system plays an integral role in the development and progression of a range
of disease conditions, which has impelled medical researchers and clinicians to design …