[HTML][HTML] Engineering precision nanoparticles for drug delivery
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
Next‐generation vaccines: nanoparticle‐mediated DNA and mRNA delivery
Nucleic acid vaccines are a method of immunization aiming to elicit immune responses akin
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
to live attenuated vaccines. In this method, DNA or messenger RNA (mRNA) sequences are …
Material design for lymph node drug delivery
A significant fraction of the total immune cells in the body are located in several hundred
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
lymph nodes, in which lymphocyte accumulation, activation and proliferation are organized …
[HTML][HTML] Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy
X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive Materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …
various fields due to a wide range of treatments applications, as demonstrated in preclinical …
[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …
[HTML][HTML] Emerging vaccine nanotechnology: from defense against infection to sniping cancer
Looking retrospectively at the development of humanity, vaccination is an unprecedented
medical landmark that saves lives by harnessing the human immune system. During the …
medical landmark that saves lives by harnessing the human immune system. During the …
Mesoporous silica as a versatile platform for cancer immunotherapy
Immunotherapy has been recognized for decades as a promising therapeutic method for
cancer treatment. To enhance host immune responses against cancer, antigen‐presenting …
cancer treatment. To enhance host immune responses against cancer, antigen‐presenting …
[HTML][HTML] Bacterial outer membrane vesicle based versatile nanosystem boosts the efferocytosis blockade triggered tumor-specific immunity
WR Zhuang, Y Wang, W Nie, Y Lei, C Liang… - Nature …, 2023 - nature.com
Efferocytosis inhibition is emerging as an attractive strategy for antitumor immune therapy
because of the subsequent leak of abundant immunogenic contents. However, the practical …
because of the subsequent leak of abundant immunogenic contents. However, the practical …
Nanovaccine‐based strategies to overcome challenges in the whole vaccination cascade for tumor immunotherapy
L Qin, H Zhang, Y Zhou, CS Umeshappa, H Gao - Small, 2021 - Wiley Online Library
Nanovaccine‐based immunotherapy (NBI) has received greater attention recently for its
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …
Lymphatic targeting by albumin-hitchhiking: applications and optimisation
M Abdallah, OO Müllertz, IK Styles, A Mörsdorf… - Journal of Controlled …, 2020 - Elsevier
The lymphatic system plays an integral role in the development and progression of a range
of disease conditions, which has impelled medical researchers and clinicians to design …
of disease conditions, which has impelled medical researchers and clinicians to design …