[HTML][HTML] Brain alarm by self-extracellular nucleic acids: From neuroinflammation to neurodegeneration

R Kunze, S Fischer, HH Marti, KT Preissner - Journal of Biomedical …, 2023 - Springer
Neurological disorders such as stroke, multiple sclerosis, as well as the neurodegenerative
diseases Parkinson's or Alzheimer's disease are accompanied or even powered by danger …

MALAT1 lncRNA and Parkinson's Disease: The role in the Pathophysiology and Significance for Diagnostic and Therapeutic Approaches

M Abrishamdar, MS Jalali, M Rashno - Molecular neurobiology, 2022 - Springer
Parkinson's disease (PD) is the second most common age-related neurodegenerative
disorder. PD is characterized by progressive loss of dopamine-producing neurons in the …

[HTML][HTML] Astrocytic MicroRNAs and transcription factors in Alzheimer's disease and therapeutic interventions

A Nassar, T Kodi, S Satarker, P Chowdari Gurram… - Cells, 2022 - mdpi.com
Astrocytes are important for maintaining cholesterol metabolism, glutamate uptake, and
neurotransmission. Indeed, inflammatory processes and neurodegeneration contribute to …

Insights into lncRNAs in Alzheimer's disease mechanisms

D Li, J Zhang, X Li, Y Chen, F Yu, Q Liu - RNA biology, 2021 - Taylor & Francis
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most
common dementia among the elderly. The pathophysiology of AD is characterized by two …

α‐Synuclein antisense transcript SNCA‐AS1 regulates synapses‐and aging‐related genes suggesting its implication in Parkinson's disease

F Rey, C Pandini, L Messa, R Launi, B Barzaghini… - Aging …, 2021 - Wiley Online Library
SNCA protein product, α‐synuclein, is widely renowned for its role in synaptogenesis and
implication in both aging and Parkinson's disease (PD), but research efforts are still needed …

Antioxidative role of Traditional Chinese Medicine in Parkinson's disease

F Muhammad, Y Liu, Y Zhou, H Yang, H Li - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Neuroprotective Traditional Chinese Medicine
(TCM) has been practiced in alternative medicine from early days. TCM-derived …

Deficiency of NEAT1 prevented MPP+-induced inflammatory response, oxidative stress and apoptosis in dopaminergic SK-N-SH neuroblastoma cells via miR-1277 …

S Zhou, D Zhang, J Guo, Z Chen, Y Chen, J Zhang - Brain Research, 2021 - Elsevier
Noncoding RNAs including long noncoding RNAs (lncRNAs) and microRNAs (miRNAs)
have been documented to play prominent role in neurodegenerative diseases including …

lncRNA NEAT1 prompts autophagy and apoptosis in MPTP-induced Parkinson's disease by impairing miR-374c-5p

L Dong, Y Zheng, L Gao, X Luo - Acta biochimica et biophysica …, 2021 - academic.oup.com
Long non-coding RNAs (lncRNAs) play biological roles in brain disorder and
neurodegenerative diseases. As the functions of lncRNA NEAT1 in Parkinson's disease …

[HTML][HTML] Inhibition of long non-coding RNA HOXA11-AS against neuroinflammation in Parkinson's disease model via targeting miR-124-3p mediated FSTL1/NF-κB …

H Cao, X Han, Y Jia, B Zhang - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Background: Studies have revealed that lncRNA HOXA11-AS contributes to regulating
inflammation, while the role of HOXA11-AS in Parkinson's disease (PD) remains unclear …

[HTML][HTML] Regulatory role of long non coding RNAs (lncRNAs) in neurological disorders: From novel biomarkers to promising therapeutic strategies

N Bhattacharyya, V Pandey, M Bhattacharyya… - Asian journal of …, 2021 - Elsevier
Long non coding RNAs (lncRNAs) are non-protein or low-protein coding transcripts that
contain more than 200 nucleotides. They representing a large share of the cell's …