Computational fluid dynamics with imaging of cleared tissue and of in vivo perfusion predicts drug uptake and treatment responses in tumours

A d'Esposito, PW Sweeney, M Ali, M Saleh… - Nature Biomedical …, 2018 - nature.com
Understanding the uptake of a drug by diseased tissue, and the drug's subsequent
spatiotemporal distribution, are central factors in the development of effective targeted …

Diffuse reflectance from a finite blood medium: applications to the modeling of fiber optic catheters

L Reynolds, C Johnson, A Ishimaru - Applied optics, 1976 - opg.optica.org
The scattering and absorption of light by randomly oriented, discretely scattering, red blood
cells imbedded in a homogeneous plasma medium can be described by the P1 …

Role of light scatterng in whole blood oximetry

JM Steinke, AP Shepherd - IEEE transactions on biomedical …, 1986 - ieeexplore.ieee.org
We investigated the role of light scattering in whole blood oximetry by transmission
spectrophotometry. To delineate the role of scattering and absorbance in the measurement …

Pulse oximetry: Theoretical and experimental models

JP De Kock, L Tarassenko - Medical and Biological Engineering and …, 1993 - Springer
In the paper a pulse oximetry model is developed using an approach which combines both
theoretical and empirical modelling. The optical properties of whole blood are measured as …

Photoplethysmography-fundamental aspects of the optical properties of blood in motion

VC Roberts - Transactions of the Institute of Measurement …, 1982 - journals.sagepub.com
This paper outlines a simplified theory to explain the behaviour of photoelectric
plethysmographs used for the measurement of blood flow in the skin. The paper reports the …

Hemoscan™: A Dialysis Machine-Integrated Blood Volume Monitor

F Paolini, E Mancini, A Bosetto… - … International journal of …, 1995 - journals.sagepub.com
We describe an opto-electronic device capable of measuring the hemoglobin concentration
(Hgb) non-invasively and continuously, hence the percentage changes in blood volume …

Transport calculations for light scattering in blood

GD Pedersen, NJ McCormick, LO Reynolds - Biophysical journal, 1976 - cell.com
In vivo measurement of the oxygen saturation levels in blood may be obtained from relative
amounts of backscattered monochromatic light at two different wavelengths, as measured …

Using in vivo bioluminescence imaging to shed light on cancer biology

SH Thorne, CH Contag - Proceedings of the IEEE, 2005 - ieeexplore.ieee.org
Luciferases are light-emitting enzymes that have been used as reporters of biological
function for several decades, and have more recently been used as reporters for the study of …

In vivo photometric analysis of hemoglobin

RN Pittman - Annals of Biomedical Engineering, 1986 - Springer
Since virtually all the oxygen carried by blood at normal hematocrit is reversibly bound to red
blood cell hemoglobin, the distribution of oxygen within the microcirculation can be …

Scattering effect for relative blood volume monitoring during hemodialysis

L Zhou, Q Li, S Wei, S Wang, J Cui, G Wang… - Sensors and Actuators A …, 2024 - Elsevier
The long-term survival rate of hemodialysis patients is limited by hemodialysis-related
complications, which are attributed to the inappropriate level of relative blood volume (RBV) …