[HTML][HTML] Pathophysiology and current drug treatments for post-stroke depression: a review

D Frank, BF Gruenbaum, A Zlotnik… - International Journal of …, 2022 - mdpi.com
Post-stroke depression (PSD) is a biopsychosocial disorder that affects individuals who
have suffered a stroke at any point. PSD has a 20 to 60 percent reported prevalence among …

[HTML][HTML] Celecoxib for mood disorders: a systematic review and meta-analysis of randomized controlled trials

A Gędek, Z Szular, AZ Antosik, P Mierzejewski… - Journal of Clinical …, 2023 - mdpi.com
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory
parameters have not yet been comprehensively evaluated. The aim of this study was to …

[HTML][HTML] Biology of cyclooxygenase-2: An application in depression therapeutics

Y He, Y Han, X Liao, M Zou, Y Wang - Frontiers in Psychiatry, 2022 - frontiersin.org
Depressive Disorder is a common mood disorder or affective disorder that is dominated by
depressed mood. It is characterized by a high incidence and recurrence. The onset of …

[HTML][HTML] Altered hippocampal subfield volumes in major depressive disorder with and without anhedonia

C Wu, L Jia, Q Mu, Z Fang, HJAS Hamoudi, M Huang… - BMC psychiatry, 2023 - Springer
Background Previous neuroimaging findings have demonstrated the association between
anhedonia and the hippocampus. However, few studies have focused on the structural …

[HTML][HTML] Meloxicam Targets COX-2/NOX1/NOX4/Nrf2 Axis to Ameliorate the Depression-like Neuropathology Induced by Chronic Restraint Stress in Rats

HH Arab, A Khames, MK Mohammad, SE Alsufyani… - Pharmaceuticals, 2023 - mdpi.com
Meloxicam has shown significant neuroprotection in experimental models of stroke,
Alzheimer's disease, and Parkinson's disease. However, the potential of meloxicam to treat …

[HTML][HTML] Involvement of inflammatory responses in the brain to the onset of major depressive disorder due to stress exposure

S Miyata, Y Ishino, S Shimizu… - Frontiers in Aging …, 2022 - frontiersin.org
Major depressive disorder is a multifactorial disease affected by several environmental
factors. Although several potential onset hypotheses have been identified, the molecular …

[HTML][HTML] The dangerous “West Coast Swing” by hyperglycaemia and chronic stress in the mouse hippocampus: Role of kynurenine catabolism

M Gliozzi, AR Coppoletta, A Cardamone… - Pharmacological …, 2024 - Elsevier
Growing epidemiological studies highlight a bi-directional relationship between depressive
symptoms and diabetes mellitus. However, the detrimental impact of their co-existence on …

Pro-inflammatory cytokines in stress-induced depression: Novel insights into mechanisms and promising therapeutic strategies

J Chang, T Jiang, X Shan, M Zhang, Y Li, X Qi… - Progress in Neuro …, 2024 - Elsevier
Stress-mediated depression is one of the common psychiatric disorders with a high
prevalence and suicide rate, there is a lack of effective treatment. Accordingly, effective …

[HTML][HTML] BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat ketamine models resembling “negative-like” symptoms of schizophrenia

A Zemba Cilic, M Zemba, M Cilic, S Strbe, S Ilic… - Biomedicines, 2022 - mdpi.com
We attempted throughout the NO-system to achieve the particular counteraction of the
ketamine-induced resembling “negative-like” schizophrenia symptoms in rats using …

[HTML][HTML] The antidepressive mechanism of Longya Lilium combined with Fluoxetine in mice with depression-like behaviors

H Ma, H Huang, C Li, S Li, J Gan, C Lian… - npj Systems Biology and …, 2024 - nature.com
Traditional Chinese medicine is one of the most commonly used complementary and
alternative medicine therapies for depression. Integrated Chinese-western therapies have …