[HTML][HTML] Pathophysiology and current drug treatments for post-stroke depression: a review
Post-stroke depression (PSD) is a biopsychosocial disorder that affects individuals who
have suffered a stroke at any point. PSD has a 20 to 60 percent reported prevalence among …
have suffered a stroke at any point. PSD has a 20 to 60 percent reported prevalence among …
[HTML][HTML] Celecoxib for mood disorders: a systematic review and meta-analysis of randomized controlled trials
A Gędek, Z Szular, AZ Antosik, P Mierzejewski… - Journal of Clinical …, 2023 - mdpi.com
The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory
parameters have not yet been comprehensively evaluated. The aim of this study was to …
parameters have not yet been comprehensively evaluated. The aim of this study was to …
[HTML][HTML] Biology of cyclooxygenase-2: An application in depression therapeutics
Y He, Y Han, X Liao, M Zou, Y Wang - Frontiers in Psychiatry, 2022 - frontiersin.org
Depressive Disorder is a common mood disorder or affective disorder that is dominated by
depressed mood. It is characterized by a high incidence and recurrence. The onset of …
depressed mood. It is characterized by a high incidence and recurrence. The onset of …
[HTML][HTML] Altered hippocampal subfield volumes in major depressive disorder with and without anhedonia
C Wu, L Jia, Q Mu, Z Fang, HJAS Hamoudi, M Huang… - BMC psychiatry, 2023 - Springer
Background Previous neuroimaging findings have demonstrated the association between
anhedonia and the hippocampus. However, few studies have focused on the structural …
anhedonia and the hippocampus. However, few studies have focused on the structural …
[HTML][HTML] Meloxicam Targets COX-2/NOX1/NOX4/Nrf2 Axis to Ameliorate the Depression-like Neuropathology Induced by Chronic Restraint Stress in Rats
Meloxicam has shown significant neuroprotection in experimental models of stroke,
Alzheimer's disease, and Parkinson's disease. However, the potential of meloxicam to treat …
Alzheimer's disease, and Parkinson's disease. However, the potential of meloxicam to treat …
[HTML][HTML] Involvement of inflammatory responses in the brain to the onset of major depressive disorder due to stress exposure
S Miyata, Y Ishino, S Shimizu… - Frontiers in Aging …, 2022 - frontiersin.org
Major depressive disorder is a multifactorial disease affected by several environmental
factors. Although several potential onset hypotheses have been identified, the molecular …
factors. Although several potential onset hypotheses have been identified, the molecular …
[HTML][HTML] The dangerous “West Coast Swing” by hyperglycaemia and chronic stress in the mouse hippocampus: Role of kynurenine catabolism
M Gliozzi, AR Coppoletta, A Cardamone… - Pharmacological …, 2024 - Elsevier
Growing epidemiological studies highlight a bi-directional relationship between depressive
symptoms and diabetes mellitus. However, the detrimental impact of their co-existence on …
symptoms and diabetes mellitus. However, the detrimental impact of their co-existence on …
Pro-inflammatory cytokines in stress-induced depression: Novel insights into mechanisms and promising therapeutic strategies
J Chang, T Jiang, X Shan, M Zhang, Y Li, X Qi… - Progress in Neuro …, 2024 - Elsevier
Stress-mediated depression is one of the common psychiatric disorders with a high
prevalence and suicide rate, there is a lack of effective treatment. Accordingly, effective …
prevalence and suicide rate, there is a lack of effective treatment. Accordingly, effective …
[HTML][HTML] BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat ketamine models resembling “negative-like” symptoms of schizophrenia
A Zemba Cilic, M Zemba, M Cilic, S Strbe, S Ilic… - Biomedicines, 2022 - mdpi.com
We attempted throughout the NO-system to achieve the particular counteraction of the
ketamine-induced resembling “negative-like” schizophrenia symptoms in rats using …
ketamine-induced resembling “negative-like” schizophrenia symptoms in rats using …
[HTML][HTML] The antidepressive mechanism of Longya Lilium combined with Fluoxetine in mice with depression-like behaviors
H Ma, H Huang, C Li, S Li, J Gan, C Lian… - npj Systems Biology and …, 2024 - nature.com
Traditional Chinese medicine is one of the most commonly used complementary and
alternative medicine therapies for depression. Integrated Chinese-western therapies have …
alternative medicine therapies for depression. Integrated Chinese-western therapies have …