[HTML][HTML] Towards enabling a cardiovascular digital twin for human systemic circulation using inverse analysis

NK Chakshu, I Sazonov, P Nithiarasu - Biomechanics and modeling in …, 2021 - Springer
An exponential rise in patient data provides an excellent opportunity to improve the existing
health care infrastructure. In the present work, a method to enable cardiovascular digital twin …

Beyond CFD: Emerging methodologies for predictive simulation in cardiovascular health and disease

EL Schwarz, L Pegolotti, MR Pfaller… - Biophysics Reviews, 2023 - pubs.aip.org
Physics-based computational models of the cardiovascular system are increasingly used to
simulate hemodynamics, tissue mechanics, and physiology in evolving healthy and …

Learning reduced-order models for cardiovascular simulations with graph neural networks

L Pegolotti, MR Pfaller, NL Rubio, K Ding… - Computers in Biology …, 2024 - Elsevier
Reduced-order models based on physics are a popular choice in cardiovascular modeling
due to their efficiency, but they may experience loss in accuracy when working with …

[HTML][HTML] Modeling reactive hyperemia to Better Understand and assess microvascular function: a review of techniques

A Coccarelli, MD Nelson - Annals of Biomedical Engineering, 2023 - Springer
Reactive hyperemia is a well-established technique for the non-invasive evaluation of the
peripheral microcirculatory function, measured as the magnitude of limb re-perfusion after a …

Automated generation of 0D and 1D reduced‐order models of patient‐specific blood flow

MR Pfaller, J Pham, A Verma, L Pegolotti… - … journal for numerical …, 2022 - Wiley Online Library
Abstract Three‐dimensional (3D) cardiovascular fluid dynamics simulations typically require
hours to days of computing time on a high‐performance computing cluster. One …

[HTML][HTML] Machine learning augmented reduced-order models for FFR-prediction

FE Fossan, LO Müller, J Sturdy, AT Bråten… - Computer methods in …, 2021 - Elsevier
Computational predictions in cardiovascular medicine have largely relied on explicit models
derived from physical and physiological principles. Recently, the application of artificial …

A semi‐active human digital twin model for detecting severity of carotid stenoses from head vibration—A coupled computational mechanics and computer vision …

NK Chakshu, J Carson, I Sazonov… - … journal for numerical …, 2019 - Wiley Online Library
In this work, we propose a methodology to detect the severity of carotid stenosis from a video
of a human face with the help of a coupled blood flow and head vibration model. This semi …

[HTML][HTML] Comparison of 1D and 3D models for the estimation of fractional flow reserve

PJ Blanco, CA Bulant, LO Müller, GDM Talou… - Scientific reports, 2018 - nature.com
In this work we propose to validate the predictive capabilities of one-dimensional (1D) blood
flow models with full three-dimensional (3D) models in the context of patient-specific …

Non‐invasive coronary CT angiography‐derived fractional flow reserve: a benchmark study comparing the diagnostic performance of four different computational …

JM Carson, S Pant, C Roobottom… - … journal for numerical …, 2019 - Wiley Online Library
Non‐invasive coronary computed tomography (CT) angiography‐derived fractional flow
reserve (cFFR) is an emergent approach to determine the functional relevance of obstructive …

[图书][B] Personalized Computational Hemodynamics: Models, Methods, and Applications for Vascular Surgery and Antitumor Therapy

Y Vassilevski, M Olshanskii, S Simakov, A Kolobov… - 2020 - books.google.com
Personalized Computational Hemodynamics: Models, Methods, and Applications for
Vascular Surgery and Antitumor Therapy offers practices and advances surrounding the …