A nonconventional archaeal fluorinase identified by in silico mining for enhanced fluorine biocatalysis
Fluorinases, the only enzymes known to catalyze the transfer of fluorine to an organic
molecule, are essential catalysts for the biological synthesis of valuable organofluorines …
molecule, are essential catalysts for the biological synthesis of valuable organofluorines …
Recent advances in fluorinated products biosynthesis
S Shi, J Tian, Y Luo - Bioresource Technology Reports, 2022 - Elsevier
The introduction of fluorine to the drug molecules endows the compounds with better
metabolic stability and bioavailability. However, naturally occurring fluorides are rare and …
metabolic stability and bioavailability. However, naturally occurring fluorides are rare and …
[HTML][HTML] Synthetic metabolism for in vitro acetone biosynthesis driven by ATP regeneration
E Kozaeva, M Nieto-Domínguez, AD Hernández… - RSC Chemical …, 2022 - pubs.rsc.org
In vitro ketone production continues to be a challenge due to the biochemical features of the
enzymes involved—even when some of them have been extensively characterized (eg …
enzymes involved—even when some of them have been extensively characterized (eg …
[HTML][HTML] Biocatalytic synthesis of 2-fluoro-3-hydroxypropionic acid
W Liu, S Yuan, M Jin, M Xian - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Fluorine has become an important element for the design of synthetic molecules for use in
medicine, agriculture, and materials. The introduction of fluorine atoms into organic …
medicine, agriculture, and materials. The introduction of fluorine atoms into organic …
[HTML][HTML] Identification of Two Novel Fluorinases From Amycolatopsis sp. CA-128772 and Methanosaeta sp. PtaU1.Bin055 and a Mutant With Improved Catalytic …
X Feng, Y Cao, W Liu, M Xian - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Fluoride plays an important role in the fields of materials and medicine. Compared with
chemical synthesis, fluorinases are natural catalysts with more application potential, which …
chemical synthesis, fluorinases are natural catalysts with more application potential, which …
A Non-conventional Archaeal Fluorinase Identified by In Silico Mining Catalyzes the Fastest Natural Nucleophilic Fluorination
Fluorinases, the only enzymes known to catalyze the transfer of fluorine to an organic
molecule, are essential biocatalysts for the sustainable synthesis of valuable …
molecule, are essential biocatalysts for the sustainable synthesis of valuable …