Heart failure is a leading cause of mortality and hospitalization worldwide. Cardiac fibrosis,
resulting from the excessive deposition of collagen fibers, is a common feature across the …

Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Diabetes mellitus (DM) and cardiovascular complications are two unmet medical
emergencies that can occur together. The rising incidence of heart failure in diabetic …

Ketogenic diet (KD) alleviates refractory epilepsy and reduces seizures in children.
However, the metabolic/cell biologic mechanisms by which the KD exerts its antiepileptic …

Objectives Heart failure with preserved ejection fraction (HFpEF) is a syndrome with
significant clinical heterogeneity. Myocardial fibrosis has been considered a common …

This review focuses on the question of metabolic syndrome (MS) being a complex, but
essentially monophyletic, galaxy of associated diseases/disorders, or just a syndrome of …

Metabolic syndrome (MetS) is a cluster of factors that increase the risk of developing
diabetes, stroke, and heart failure. The pathophysiology of injury by ischemia/reperfusion …

Introduction: Skeletal muscle is a major contributor to whole-body energy homeostasis and
the utilization of fatty acids and glucose. At present, 2D cell models have been the most used …

Background The association between obesity and cardiovascular disease (CVD) in people
without traditional CVD risk factors is unclear. This study aimed to investigate the association …

BACKGROUND Left ventricular diastolic dysfunction (LVDD) is often associated with
elevated blood pressure (BP). It is prevalent among hypertensive patients. Additionally …