Cancer therapy selects for cancer cells resistant to treatment, a process that is fundamentally
evolutionary. To what extent, however, is the evolutionary perspective employed in research …

The most important prognostic variables of cervical carcinoma are FIGO stage, lymph node
status and clinical-pathological features of primary tumor. Recently, there has been …

Abstract Multi-target EGFR, HER2, VEGFR-2 and PDGFR is an improved strategy for the
treatment of solid tumors. This work deals with synthesis of an array of new 6-benzoyl …

Aim: The survival in locally advanced cervical cancer remains low. We evaluated the role of
neoadjuvant chemotherapy (NACT), chemoradiotherapy (CRT), followed by gefitinib …

Cervical cancer is the third most common cancer worldwide, and the development of new
diagnosis, prognostic, and treatment strategies is a major interest for public health. Cisplatin …

Purpose: EGFR is frequently overexpressed in cervical cancer, suggesting EGFR blockade
as a promising treatment approach. Cetuximab, an anti EGFR antibody, used conjointly with …

Clinical trials have provided conflicting results regarding whether epidermal growth factor
receptor (EGFR) overexpression predicts poor survival in cervical cancer patients. In this …

Cervical cancer is the third most prevalent cancer among women worldwide. Theanine from
tea and its derivatives show some anticancer activities. However, the role of theanine and its …

Prognostic factors and therapeutic targets are needed for the patients with cervical
adenocarcinoma because they have a poor prognosis. Recently, co-expression of multiple …

Objective Resistance to chemo-radiation therapy is a substantial obstacle that compromises
treatment of advanced cervical cancer. The objective of this study was to investigate if a …