Transposable elements (TE), small mobile genetic elements unable to exist independently
of the host genome, were initially believed to be exclusively deleterious genomic parasites …

The IS 6 family of bacterial and archaeal insertion sequences, first identified in the early
1980s, has proved to be instrumental in the rearrangement and spread of multiple antibiotic …

We have divided this review into two major sections. In one, we have attempted to present
an overview of our current understanding of prokaryotic insertion sequences (IS), their …

Many genomic sequences have been recently published for bacteria that can replicate only
within eukaryotic hosts. Comparisons of genomic features with those of closely related …

This chapter is an update of a survey of insertion sequences (ISs) published in 1998.
Researchers have retained the same basic structure: a first section including some key …

The rapidly emerging phenomenon of antibiotic resistance threatens to substantially reduce
the efficacy of available antibacterial therapies. Dissemination of resistance, even between …

The nitroaromatic explosive 2, 4, 6-trinitrotoluene (TNT) is a highly toxic and persistent
environmental pollutant. Since physicochemical methods for remediation are poorly …

Mycobacterium avium subsp. paratuberculosis is a pathogen that causes chronic
inflammation of the intestine in many animals, including primates, and is implicated in …

Pseudomonas aeruginosa is the leading cause of infection in burn patients. The increasing
carbapenem resistance of P. aeruginosa has become a serious challenge to clinicians. The …

The mobile insertion sequence, IS6110, is an important marker in tracking of Mycobacterium
tuberculosis strains. Here, we demonstrate that IS6110 can upregulate downstream genes …