Macroevolution by transposition: drastic modification of DNA recognition by a type I restriction enzyme following Tn5 transposition.

J Meister, M MacWilliams, P Hübner, H Jütte… - The EMBO …, 1993 - embopress.org
We have characterized a novel mutant of EcoDXXI, a type IC DNA restriction and
modification (R‐M) system, in which the specificity has been altered due to a Tn5 insertion …

Restriction enzymes and their isoschizomers

RJ Roberts - Nucleic acids research, 1987 - ncbi.nlm.nih.gov
The database shown in these Tables is available online through the BIONET computer
resource. A version corresponding to the printed text is located in the file< ROBERTS> …

Generation of DNA cleavage specificities of type II restriction endonucleases by reassortment of target recognition domains

S Jurėnaitė-Urbanavičienė… - Proceedings of the …, 2007 - National Acad Sciences
Type II restriction endonucleases (REases) cleave double-stranded DNA at specific sites
within or close to their recognition sequences. Shortly after their discovery in 1970, REases …

[HTML][HTML] Effect of site-specific methylation on DNA modification methyltransferases and restriction endonucleases

M McClelland, M Nelson - Nucleic acids research, 1992 - ncbi.nlm.nih.gov
Effect of m5CG and m5CNG on restriction endonucleases Enzymes that are not sensitive to
site-specific methylation are particularly useful for achieving complete digestion …

Conservation of organization in the specificity polypeptides of two families of type I restriction enzymes

P Kannan, GM Cowan, AS Daniel, AAF Gann… - Journal of molecular …, 1989 - Elsevier
We have identified the recognition sequence for the Citrobacter freundii restriction
endonuclease CfrA, a member of the A-family of type I RM enzymes. This bipartite target …

[HTML][HTML] Restriction enzymes and their isoschizomers

RJ Roberts - Nucleic acids research, 1989 - ncbi.nlm.nih.gov
Restriction enzymes and their isoschizomers - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …

The DNA recognition subunit of the type IB restriction-modification enzyme EcoAI tolerates circular permutions of its polypeptide chain

P Janscak, TA Bickle - Journal of molecular biology, 1998 - Elsevier
The DNA specificity subunit (HsdS) of type I restriction-modification enzymes is composed of
two independent target recognition domains and several regions whose amino acid …

ATP-dependent restriction enzymes

DN Rao, S Saha, V Krishnamurthy - 2000 - Elsevier
The phenomenon of restriction and modification (RM) was first observed in the course of
studies on bacteriophages in the early 1950s. It was only in the 1960s that work of Arber and …

DNA recognition by a new family of type I restriction enzymes: a unique relationship between two different DNA specificities.

C Price, JC Shepherd, TA Bickle - The EMBO Journal, 1987 - embopress.org
The DNA sequences recognized by the allelic type I restriction enzymes EcoR124 and
EcoR124/3 were determined. EcoR124 recognizes 5′‐GAA (N6) RTCG‐3′ and …

Evolution of sequence specificity in a restriction endonuclease by a point mutation

M Saravanan, K Vasu… - Proceedings of the …, 2008 - National Acad Sciences
Restriction endonucleases (REases) protect bacteria from invading foreign DNAs and are
endowed with exquisite sequence specificity. REases have originated from the ancestral …