Osteoporosis is a widespread systemic disease characterized by a decrease in bone mass
and an imbalance of the microarchitecture of bone tissue. Experimental and clinical studies …

With the aging world population, the prevalence of aging‐related disorders is on the rise.
Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's …

Ongoing research has highlighted the significance of the cross-play of macrophages and
mesenchymal stem cells (MSCs). Lysine-specific demethylase 6B (KDM6B) has been …

Rheumatoid arthritis (RA) represents one of the best examples of circadian fluctuations in
disease severity. Patients with RA experience stiffness, pain, and swelling in afflicted joints …

Melatonin is an important endogenous hormone that modulates homeostasis in the
microenvironment. Recent studies have indicated that serum melatonin levels are closely …

Brain and muscle aryl-hydrocarbon receptor nuclear translocator like protein1 (BMAL1), a
core component of circadian oscillation, is involved in many physiological activities …

The circadian clock regulates many key physiological processes such as the sleep–wake
cycle, hormone release, cardiovascular health, glucose metabolism and body temperature …

Abstract Purpose of Review Review recent literature investigating the relationship between
bone health and sleep/circadian disruptions (eg, abnormal sleep duration, night shift work) …

Alzheimer's Disease (AD) and osteoporosis are both age-related degenerative diseases.
Many studies indicate that these two diseases share common pathogenesis mechanisms. In …

Bone cells in the human body are continuously engaged in cellular metabolism, including
the interaction between bone cells, the interaction between the erythropoietic cells of the …