Transposable elements are abundant in the human genome, and great strides have been
made in pinpointing variations in these repetitive sequences using whole-genome …

Endogenous retroviruses (ERVs) are emerging as promising therapeutic targets in cancer.
As remnants of ancient retroviral infections, ERV-derived regulatory elements coordinate …

Transposable elements (TEs) help shape the structure and function of the human genome.
When inserted into some locations, TEs may disrupt gene regulation and cause diseases …

Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections
in the evolution of primates and account for about 8% of the human genome. They were …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Background Despite an impressive effort in clinical research, no standard therapeutic
approach for coronavirus disease 2019 (COVID-19) patients has been established …

Our genome is a historic record of successive invasions of mobile genetic elements. Like
other eukaryotes, we have evolved mechanisms to limit their propagation and minimize the …

Acute myeloid leukemia (AML) is characterised by a series of genetic and epigenetic
alterations that result in deregulation of transcriptional networks. One understudied source of …

The human endogenous retrovirus type-H (HERVH) family is expressed in the
preimplantation embryo. A subset of these elements are specifically transcribed in …

Transposable elements (TEs) are recognized as major players in genome plasticity and
evolution. The high abundance of TEs in the human genome, especially the Alu and Long …