Novel and innovative approaches are essential in developing new treatments and improving
clinical outcomes in patients with ischemic stroke. Remote ischemic conditioning (RIC) is a …

Sirtuins are a family of highly evolutionarily conserved nicotinamide adenine nucleotide‐
dependent histone deacetylases. Sirtuin‐3 (SIRT 3) is a member of the sirtuin family that is …

Stroke is one of the main causes of neurological disability worldwide and the second cause
of death in people over 65 years old, resulting in great economic and social burden …

Bone mass loss around prostheses is a major cause of implant failure, especially in
postmenopausal osteoporosis patients. In osteoporosis, excess oxidative stress largely …

Shikonin, isolated from the roots of herbal plant Lithospermum erythrorhizon, is a
naphthoquinone. It has been reported to exert beneficial anti-inflammatory effects and anti …

Remote ischemic conditioning (RIC) is a promising therapeutic approach for ischemic stroke
patients. It has been proven that RIC reduces infarct size and improves functional outcomes …

Remote ischaemic conditioning (RIC) is achieved by repeated transient ischaemia of a
distant organ/limb and is neuroprotective in experimental ischaemic stroke. However, the …

Ischemic conditioning is defined as a transient and subcritical period of ischemia integrated
in an experimental paradigm that involves a stimulus of injurious ischemia, activating …

Alcohol and drug overdoses cause liver diseases such as cirrhosis, hepatitis, and liver
cancer globally. In particular, an overdose of acetaminophen (APAP), which is generally …

Limb remote ischemic postconditioning (LRIP) has been confirmed to reduce the ischemia-
reperfusion injury but its mechanisms are still not clear. This study clarified the mechanism of …