The population genetics of pathogenic Escherichia coli

E Denamur, O Clermont, S Bonacorsi… - Nature Reviews …, 2021 - nature.com
Escherichia coli is a commensal of the vertebrate gut that is increasingly involved in various
intestinal and extra-intestinal infections as an opportunistic pathogen. Numerous pathotypes …

[HTML][HTML] Alteration of gut microbiota in inflammatory bowel disease (IBD): cause or consequence? IBD treatment targeting the gut microbiome

I Khan, N Ullah, L Zha, Y Bai, A Khan, T Zhao, T Che… - Pathogens, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic complex inflammatory gut pathological
condition, examples of which include Crohn's disease (CD) and ulcerative colitis (UC) …

[HTML][HTML] The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen

P Pokharel, S Dhakal, CM Dozois - Microorganisms, 2023 - mdpi.com
Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …

Microbial network disturbances in relapsing refractory Crohn's disease

B Yilmaz, P Juillerat, O Øyås, C Ramon, FD Bravo… - Nature medicine, 2019 - nature.com
Inflammatory bowel diseases (IBD) can be broadly divided into Crohn's disease (CD) and
ulcerative colitis (UC) from their clinical phenotypes. Over 150 host susceptibility genes have …

Adherent-invasive Escherichia coli in inflammatory bowel disease

C Palmela, C Chevarin, Z Xu, J Torres, G Sevrin… - Gut, 2018 - gut.bmj.com
Intestinal microbiome dysbiosis has been consistently described in patients with IBD. In the
last decades, Escherichia coli, and the adherent-invasive E coli (AIEC) pathotype in …

[HTML][HTML] Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesis

LCH Yu - Journal of biomedical science, 2018 - Springer
Inflammatory bowel disease (IBD) is a multifactorial disease which arises as a result of the
interaction of genetic, environmental, barrier and microbial factors leading to chronic …

[HTML][HTML] Interactions of intestinal bacteria with components of the intestinal mucus

JF Sicard, G Le Bihan, P Vogeleer… - Frontiers in cellular …, 2017 - frontiersin.org
The human gut is colonized by a variety of large amounts of microbes that are collectively
called intestinal microbiota. Most of these microbial residents will grow within the mucus …

Antibiotics as deep modulators of gut microbiota: between good and evil

G Ianiro, H Tilg, A Gasbarrini - Gut, 2016 - gut.bmj.com
The recent increase in our knowledge of human gut microbiota has changed our view on
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …

The microbiome in inflammatory bowel disease: current status and the future ahead

AD Kostic, RJ Xavier, D Gevers - Gastroenterology, 2014 - Elsevier
Studies of the roles of microbial communities in the development of inflammatory bowel
disease (IBD) have reached an important milestone. A decade of genome-wide association …

Recent advances in understanding enteric pathogenic Escherichia coli

MA Croxen, RJ Law, R Scholz… - Clinical microbiology …, 2013 - Am Soc Microbiol
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …