Recurrent Clostridioides difficile Infection: Current Clinical Management and Microbiome-Based Therapies

P Berry, S Khanna - BioDrugs, 2023 - Springer
Clostridioides difficile is one of the most important causes of healthcare-associated diarrhea.
The high incidence and recurrence rates of C. difficile infection, as well as its associated …

Clostridioides difficile resistance to antibiotics, including post-COVID-19 data

L Boyanova, G Dimitrov, R Gergova… - Expert Review of …, 2023 - Taylor & Francis
ABSTRACT Introduction Updating data on Clostridioides difficile antibiotic resistance is
important for treatment improvement of C. difficile infections (CDIs). Areas covered Results …

Long-term impact of the COVID-19 pandemic on in-hospital antibiotic consumption and antibiotic resistance: a time series analysis (2015–2021)

M Meschiari, L Onorato, E Bacca, G Orlando… - Antibiotics, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19)-pandemic-related overload of health systems
has compromised the application of antimicrobial stewardship (AS) models and infection …

The burden of CDI in the United States: a multifactorial challenge

P Feuerstadt, N Theriault, G Tillotson - BMC Infectious Diseases, 2023 - Springer
Clostridioides difficile infection (CDI) affects approximately 500,000 patients annually in the
United States, of these around 30,000 will die. CDI carries significant burdens including …

Clostridioides difficile spores tolerate disinfection with sodium hypochlorite disinfectant and remain viable within surgical scrubs and gown fabrics

H Ahmed, LT Joshi - Microbiology, 2023 - microbiologyresearch.org
Clostridioides difficile is the most common cause of antibiotic-associated diarrhoea globally.
Its spores have been implicated in the prevalence of C. difficile infection due to their …

Microbiome-Related and Infection Control Approaches to Primary and Secondary Prevention of Clostridioides difficile Infections

LV McFarland, EJC Goldstein, R Kullar - Microorganisms, 2023 - mdpi.com
Clostridioides difficile infections (CDIs) have decreased in the past years, but since 2021,
some hospitals have reported an increase in CDI rates. CDI remains a global concern and …

The impact of clostridioides difficile infection in hospitalized patients: what changed during the pandemic?

A Boeriu, A Roman, D Dobru, M Stoian, S Voidăzan… - Diagnostics, 2022 - mdpi.com
(1) Background: Clostridioides difficile (C. difficile) and SARS-CoV-2 coronavirus represent
significant health threats. Our study focused on the impact of concurrent infections on patient …

Clostridioides difficile Infection in Hospitalized Patients—A Retrospective Epidemiological Study

F Fonseca, M Forrester, AM Advinha, A Coutinho… - Healthcare, 2023 - mdpi.com
Clostridioides difficile infection (CDI) is the main source of healthcare and antibiotic-
associated diarrhea in hospital context and long-term care units, showing significant …

Impact of the COVID-19 pandemic on Clostridioides difficile infection in a tertiary healthcare institution in Belgium

B Tossens, P Barthelme, C Briquet, L Belkhir… - Acta Clinica …, 2023 - Taylor & Francis
Objectives Clostridioides difficile infection (CDI) causes the greatest number of healthcare-
associated infectious diarrhoea. CDIs are transmitted by direct and indirect patient-to-patient …

Comparison between Symptomatic and Asymptomatic Mice after Clostridioides difficile Infection Reveals Novel Inflammatory Pathways and Contributing Microbiota

A AbdelKhalek, SK Narayanan - Microorganisms, 2022 - mdpi.com
Clostridioides difficile causes the highest number of nosocomial infections. Currently,
treatment options for C. difficile infection (CDI) are very limited, resulting in poor treatment …