Deep brain stimulation (DBS) is an effective surgical therapy for carefully selected patients
with medication refractory essential tremor (ET). The most popular anatomical targets for ET …

Human studies, in combination with animal and cellular models, support glial cells as both
major contributors to neurodegenerative diseases and promising therapeutic targets. Among …

Objective To investigate whether neurite orientation dispersion and density imaging
(NODDI) could provide the added value for detecting brain microstructural alterations in the …

Introduction Cognitive impairment (CI) is reported but is poorly explored in spinocerebellar
ataxia 2 (SCA2). This study was undertaken to evaluate and classify cognitive impairment in …

Background GAA-FGF14 ataxia (SCA27B) is a recently reported late-onset ataxia caused by
a GAA repeat expansion in intron 1 of the FGF14 gene. Initial studies revealed cerebellar …

Charcot–Marie–Tooth disease (CMT) is a genetically heterogeneous hereditary peripheral
neuropathy. Brain volumetry and diffusion tensor imaging (DTI) were performed in 47 …

Purpose Spinocerebellar ataxia type 2 (SCA2) is a progressive neurodegenerative disorder
characterized by cerebellar atrophy. However, studies to elucidate the longitudinal …

Spinocerebellar ataxias (SCAs) are a rare autosomal dominant neurodegenerative disorder.
To date, approximately 50 different subtypes of SCAs have been characterized. The …

Spinocerebellar ataxias (SCAs) are rare autosomal dominant neurodegenerative disorders
characterized by high heterogeneity regarding both their clinical manifestations and genetic …