The circadian clock in cancer development and therapy
L Fu, NM Kettner - Progress in molecular biology and translational …, 2013 - Elsevier
Most aspects of mammalian function display circadian rhythms driven by an endogenous
clock. The circadian clock is operated by genes and comprises a central clock in the brain …
clock. The circadian clock is operated by genes and comprises a central clock in the brain …
Mechanisms of RET signaling in cancer: current and future implications for targeted therapy
De-regulation of RET signaling by oncogenic mutation, gene rearrangement,
overexpression or transcriptional up-regulation is implicated in several human cancers of …
overexpression or transcriptional up-regulation is implicated in several human cancers of …
Recapitulating thyroid cancer histotypes through engineering embryonic stem cells
Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. The cell
subpopulation in the lineage hierarchy that serves as cell of origin for the different TC …
subpopulation in the lineage hierarchy that serves as cell of origin for the different TC …
Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue
S Corbetta, V Vaira, V Guarnieri… - Endocrine-related …, 2010 - erc.bioscientifica.com
Parathyroid carcinoma (PaC) is a rare cause of primary hyperparathyroidism. Though the
loss of the oncosuppressor CDC73/HRPT2 gene product, parafibromin, has been involved …
loss of the oncosuppressor CDC73/HRPT2 gene product, parafibromin, has been involved …
Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids
H Lasolle, A Schiavo, A Tourneur, P Gillotay… - Oncogene, 2024 - nature.com
Thyroid cancer is the most common endocrine malignancy and several genetic events have
been described to promote the development of thyroid carcinogenesis. Besides the effects of …
been described to promote the development of thyroid carcinogenesis. Besides the effects of …
Management of radioiodine refractory differentiated thyroid cancer: the Latin American perspective
F Pitoia, RS Scheffel, I Califano, A Gauna… - Reviews in Endocrine …, 2024 - Springer
Radioiodine (RAI) refractory differentiated thyroid cancer is an uncommon and challenging
situation that requires a multidisciplinary approach to therapeutic strategies. The definition of …
situation that requires a multidisciplinary approach to therapeutic strategies. The definition of …
Role of thyroid hormones in the neoplastic process: an overview
IM Goemann, M Romitti, ELS Meyer… - Endocrine-related …, 2017 - erc.bioscientifica.com
Thyroid hormones (TH) are critical regulators of several physiological processes, which
include development, differentiation and growth in virtually all tissues. In past decades …
include development, differentiation and growth in virtually all tissues. In past decades …
Associations of urinary phthalate metabolites with risk of papillary thyroid cancer
H Miao, X Liu, J Li, L Zhang, Y Zhao, S Liu, S Ni, Y Wu - Chemosphere, 2020 - Elsevier
Some studies have revealed thyrotoxicity of phthalates; however, associations of phthalate
exposure with papillary thyroid cancer (PTC) remain unclear. We conducted a pair-matching …
exposure with papillary thyroid cancer (PTC) remain unclear. We conducted a pair-matching …
[HTML][HTML] A distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy sensitive than papillary thyroid cancer
Both anaplastic thyroid cancer (ATC) and papillary thyroid cancer (PTC) originate from
thyroid follicular epithelial cells, but ATC has a significantly worse prognosis and shows …
thyroid follicular epithelial cells, but ATC has a significantly worse prognosis and shows …
Uncovering Actions of Type 3 Deiodinase in the Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)
RA Marschner, AC Roginski, RT Ribeiro, L Longo… - Cells, 2023 - mdpi.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) has gained worldwide
attention as a public health problem. Nonetheless, lack of enough mechanistic knowledge …
attention as a public health problem. Nonetheless, lack of enough mechanistic knowledge …