Most aspects of mammalian function display circadian rhythms driven by an endogenous
clock. The circadian clock is operated by genes and comprises a central clock in the brain …

De-regulation of RET signaling by oncogenic mutation, gene rearrangement,
overexpression or transcriptional up-regulation is implicated in several human cancers of …

Thyroid carcinoma (TC) is the most common malignancy of endocrine organs. The cell
subpopulation in the lineage hierarchy that serves as cell of origin for the different TC …

Parathyroid carcinoma (PaC) is a rare cause of primary hyperparathyroidism. Though the
loss of the oncosuppressor CDC73/HRPT2 gene product, parafibromin, has been involved …

Thyroid cancer is the most common endocrine malignancy and several genetic events have
been described to promote the development of thyroid carcinogenesis. Besides the effects of …

Radioiodine (RAI) refractory differentiated thyroid cancer is an uncommon and challenging
situation that requires a multidisciplinary approach to therapeutic strategies. The definition of …

Thyroid hormones (TH) are critical regulators of several physiological processes, which
include development, differentiation and growth in virtually all tissues. In past decades …

Some studies have revealed thyrotoxicity of phthalates; however, associations of phthalate
exposure with papillary thyroid cancer (PTC) remain unclear. We conducted a pair-matching …

Both anaplastic thyroid cancer (ATC) and papillary thyroid cancer (PTC) originate from
thyroid follicular epithelial cells, but ATC has a significantly worse prognosis and shows …

Metabolic dysfunction-associated fatty liver disease (MAFLD) has gained worldwide
attention as a public health problem. Nonetheless, lack of enough mechanistic knowledge …