Clinical trial principles and endpoint definitions for paravalvular leaks in surgical prosthesis

CE Ruiz, RT Hahn, A Berrebi, JS Borer… - European heart …, 2018 - academic.oup.com
Abstract The VARC (Valve Academic Research Consortium) for transcatheter aortic valve
replacement set the standard for selecting appropriate clinical endpoints reflecting safety …

Paravalvular leaks—from diagnosis to management

S Bernard, E Yucel - Current treatment options in cardiovascular medicine, 2019 - Springer
Purpose of review As the number of surgical and transcatheter valve replacements continue
to increase in the aging population, so does the incidence of paravalvular leak (PVL). Given …

Techniques and outcomes for the treatment of paravalvular leak

MF Eleid, AK Cabalka, JF Malouf, S Sanon… - Circulation …, 2015 - Am Heart Assoc
2 Eleid et al Techniques for Treatment of Paravalvular Leak necessary to make a definitive
diagnosis, exclude LA thrombus, evaluate prosthetic function, characterize the severity of …

Techniques and outcomes of percutaneous aortic paravalvular leak closure

M Alkhouli, M Sarraf, E Maor, S Sanon… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The aim of this study is to provide a summary of the currently applied aortic
paravalvular leak (PVL) closure techniques and describe the procedural and long-term …

[HTML][HTML] Outcomes and predictors of success and complications for paravalvular leak closure: an analysis of the SpanisH real-wOrld paravalvular LEaks closure …

E García, D Arzamendi… - …, 2017 - eurointervention.pcronline.com
Aims: The aim of the study was to assess the safety and efficacy of percutaneous closure of
paravalvular prosthetic leak (PVL) and to identify the predictors of procedural success and …

Outcomes after paravalvular leak closure: transcatheter versus surgical approaches

JA Wells, JF Condado, N Kamioka, A Dong… - JACC: Cardiovascular …, 2017 - jacc.org
Objectives: The aim of this study was to compare outcomes of transcatheter intervention (TI)
versus surgical intervention (SI) for paravalvular leak (PVL). Background: Data comparing …

[HTML][HTML] Transcatheter closure of paravalvular leaks: state of the art

I Cruz-Gonzalez, JC Rama-Merchan… - Netherlands Heart …, 2017 - Springer
Paravalvular leak (PVL) is a serious complication after surgical valve replacement or after
transcatheter aortic valve replacement. Approximately 1–5% of PVLs can lead to serious …

Transcatheter Closure or Surgery for Symptomatic Paravalvular Leaks: The Multicenter KISS Registry

A Güner, C Kırma, M Ertürk, M Türkmen… - Journal of the …, 2024 - Am Heart Assoc
Background The optimal treatment of symptomatic paravalvular leak (PVL) remains
controversial between transcatheter closure (TC) and surgery. This large‐scale study aimed …

Percutaneous paravalvular leak closure: chasing the chameleon

F Nietlispach, F Maisano, P Sorajja… - European heart …, 2016 - academic.oup.com
Paravalvular leak (PVL) occurs after both surgical and transcatheter valve replacement/
implantation. It can lead to haemolysis, heart failure and may increase the risk of …

Impact of a successful percutaneous mitral paravalvular leak closure on long-term major clinical outcomes.

Y Belahnech, GM Aguasca, BG Del Blanco… - Canadian Journal of …, 2023 - Elsevier
Background Percutaneous mitral paravalvular leak (PVL) closure techniques are an
effective and safe alternative to surgical treatment, but data regarding long-term outcomes …