Superoxide dismutases (SODs) are metalloenzymes that play a major role in antioxidant
defense against oxidative stress in the body. SOD supplementation may therefore trigger the …

Alzheimer's disease constitutes a growing cause of cognitive impairment in aging
population. Given that current treatments do not produce the desired therapeutic effects, the …

Cerebrospinal fluid (CSF) p-tau181 (tau phosphorylated at threonine 181) is an established
biomarker of Alzheimer's disease (AD), reflecting abnormal tau metabolism in the brain …

Inflammation is a pathological hallmark of Alzheimer's disease, and innate immune cells
have been shown to contribute to disease pathogenesis. In two transgenic models of …

The function of B cells in Alzheimer's disease (AD) is not fully understood. While
immunoglobulins that target amyloid beta (Aβ) may interfere with plaque formation and …

Alzheimer's disease (AD) is the most common senile dementia in the world. Although
important progress has been made in understanding the pathogenesis of AD, current …

Obesity is a multifactorial disease in which environmental conditions and several genes play
an important role in the development of this disease. Obesity is associated with …

Transgenic mouse models have been used extensively to model the cognitive impairments
arising from Alzheimer's disease (AD)-related pathology. However, less is known about the …

Alzheimer's disease (AD) involves progressive accumulation of amyloid β-peptide (Aβ) and
neurofibrillary pathologies, and glucose hypometabolism in brain regions critical for …

Alzheimer's disease (AD) can be divided into sporadic AD (SAD) and familial AD (FAD).
Most AD cases are sporadic and result from multiple etiologic factors, including …